Frozen section of lung specimens

Anna Sienko, Timothy Craig Allen, Dani S. Zander, Philip T. Cagle

Research output: Contribution to journalReview articlepeer-review

52 Scopus citations


Context. - Frozen section of lung tissue is performed to guide the surgeon in subsequent therapy. Design. - Practical experience in frozen section of the lung was reviewed in the medical literature and from the records of several academic hospitals. Results. - Most frozen sections of the lung are performed for evaluation of a solitary nodule, a mass, or the surgical margins of a resection. Frozen section may also be used to assess the adequacy of a lung wedge biopsy taken for later diagnosis of a condition. Conclusion. - The pathologic evaluation of intraoperative pulmonary lesions is indicated for the differential diagnosis of pulmonary nodules and masses, both neoplastic and nonneoplastic, surgical resection margins, and mediastinal lymph nodes. The most worrisome pitfalls involve differentiating benign reactive atypia from malignancy on frozen section.

Original languageEnglish (US)
Pages (from-to)1602-1609
Number of pages8
JournalArchives of Pathology and Laboratory Medicine
Issue number12
StatePublished - Dec 1 2005

ASJC Scopus subject areas

  • Pathology and Forensic Medicine
  • Medical Laboratory Technology


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