Frontiers of More than Moore in bioelectronics and the required metrology needs

Anthony Guiseppi-Elie, Christian Kotanen, A. Nolan Wilson

Research output: Chapter in Book/Report/Conference proceedingConference contribution

1 Scopus citations


Silicon's intersection with biology is a premise inherent in Moore's prediction. Distinct from biologically inspired molecular logic and storage devices (more Moore) are the integration of solid state electronic devices with the soft condensed state of the body (more than Moore). Developments in biomolecular recognition events per sq. cm parallel those of Moore's Law. However, challenges continue in the area of "More than Moore". Two grand challenge problems must be addressed - the biocompatibility of synthetic materials with the myriad of tissue types within the human body and the interfacing of solid state micro- and nano-electronic devices with the electronics of biological systems. Electroconductive hydrogels have been developed as soft, condensed, biomimetic but otherwise inherently electronically conductive materials to address the challenge of interfacing solid state devices with the electronics of the body, which is predominantly ionic. Nano-templated interfaces via the oriented immobilization of single walled carbon nanotubes (SWCNTs) onto metallic electrodes have engendered reagentless, direct electron transfer between biological redox enzymes and solid state electrodes. In addressing these challenges, metrology needs and opportunities are found in such widely diverse areas as single molecule counting and addressing, sustainable power requirements such as the development of implantable biofuel cells for the deployment of implantable biochips, and new manufacturing paradigms to address plura-biology needs on solid state devices.

Original languageEnglish (US)
Title of host publicationFrontiers of Characterization and Metrology for Nanoelectronics
Subtitle of host publication2011
Number of pages10
StatePublished - 2011
EventFrontiers of Characterization and Metrology for Nanoelectronics: 2011 - Grenoble, France
Duration: May 23 2011May 26 2011

Publication series

NameAIP Conference Proceedings
ISSN (Print)0094-243X
ISSN (Electronic)1551-7616


OtherFrontiers of Characterization and Metrology for Nanoelectronics: 2011


  • Moore
  • biocompatibility
  • bioelectronics
  • biointerfaces
  • bionics

ASJC Scopus subject areas

  • Physics and Astronomy(all)


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