Fractionated high-dose rate brachytherapy for intracranial gliomas

S. Woo; E. B. Butler; W. Grant; B. Berner; P. Gildenberg

doi:10.1016/0360-3016(94)90163-5

Fractionated high-dose rate brachytherapy for intracranial gliomas

S. Woo, E. B. Butler, W. Grant, B. Berner, P. Gildenberg

Research output: Contribution to journal › Article › peer-review

5 Scopus citations

Abstract

Purpose: To develop a catheter system for fractionated high-dose rate (HDR) brachytherapy for intracranial gliomas. Methods and Materials: The catheter system for stereotactic placement as well as delivery of the high-dose rate iridium-192 source wire is described. The force of the impulse wave from the source wire entering brain equivalent material was measured. Dose volume histograms for the first 5 patients treated are presented. Results: The catheter system was found to be satisfactory. The maximum force of the impulse wave was less than 1 acceleration of gravity (which is safe). The patients tolerated the treatment well with no significant problems related to the catheters being left in situ for up to 14 days. Conclusion: Based on this pilot experience a phase I dose escalating and morbidity study has been initiated.

Original language	English (US)
Pages (from-to)	247-249
Number of pages	3
Journal	International Journal of Radiation Oncology, Biology, Physics
Volume	28
Issue number	1
DOIs	https://doi.org/10.1016/0360-3016(94)90163-5
State	Published - Jan 1 1994

Keywords

Brachytherapy
Glioma
High-dose rate
Stereotactic

ASJC Scopus subject areas

Radiation
Radiology Nuclear Medicine and imaging
Oncology

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10.1016/0360-3016(94)90163-5

Cite this

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title = "Fractionated high-dose rate brachytherapy for intracranial gliomas",

abstract = "Purpose: To develop a catheter system for fractionated high-dose rate (HDR) brachytherapy for intracranial gliomas. Methods and Materials: The catheter system for stereotactic placement as well as delivery of the high-dose rate iridium-192 source wire is described. The force of the impulse wave from the source wire entering brain equivalent material was measured. Dose volume histograms for the first 5 patients treated are presented. Results: The catheter system was found to be satisfactory. The maximum force of the impulse wave was less than 1 acceleration of gravity (which is safe). The patients tolerated the treatment well with no significant problems related to the catheters being left in situ for up to 14 days. Conclusion: Based on this pilot experience a phase I dose escalating and morbidity study has been initiated.",

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T1 - Fractionated high-dose rate brachytherapy for intracranial gliomas

AU - Woo, S.

AU - Butler, E. B.

AU - Grant, W.

AU - Berner, B.

AU - Gildenberg, P.

PY - 1994/1/1

Y1 - 1994/1/1

N2 - Purpose: To develop a catheter system for fractionated high-dose rate (HDR) brachytherapy for intracranial gliomas. Methods and Materials: The catheter system for stereotactic placement as well as delivery of the high-dose rate iridium-192 source wire is described. The force of the impulse wave from the source wire entering brain equivalent material was measured. Dose volume histograms for the first 5 patients treated are presented. Results: The catheter system was found to be satisfactory. The maximum force of the impulse wave was less than 1 acceleration of gravity (which is safe). The patients tolerated the treatment well with no significant problems related to the catheters being left in situ for up to 14 days. Conclusion: Based on this pilot experience a phase I dose escalating and morbidity study has been initiated.

AB - Purpose: To develop a catheter system for fractionated high-dose rate (HDR) brachytherapy for intracranial gliomas. Methods and Materials: The catheter system for stereotactic placement as well as delivery of the high-dose rate iridium-192 source wire is described. The force of the impulse wave from the source wire entering brain equivalent material was measured. Dose volume histograms for the first 5 patients treated are presented. Results: The catheter system was found to be satisfactory. The maximum force of the impulse wave was less than 1 acceleration of gravity (which is safe). The patients tolerated the treatment well with no significant problems related to the catheters being left in situ for up to 14 days. Conclusion: Based on this pilot experience a phase I dose escalating and morbidity study has been initiated.

KW - Brachytherapy

KW - Glioma

KW - High-dose rate

KW - Stereotactic

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Fractionated high-dose rate brachytherapy for intracranial gliomas

Abstract

Keywords

ASJC Scopus subject areas

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