Fractionated high-dose rate brachytherapy for intracranial gliomas

S. Woo, E. B. Butler, W. Grant, B. Berner, P. Gildenberg

Research output: Contribution to journalArticlepeer-review

5 Scopus citations


Purpose: To develop a catheter system for fractionated high-dose rate (HDR) brachytherapy for intracranial gliomas. Methods and Materials: The catheter system for stereotactic placement as well as delivery of the high-dose rate iridium-192 source wire is described. The force of the impulse wave from the source wire entering brain equivalent material was measured. Dose volume histograms for the first 5 patients treated are presented. Results: The catheter system was found to be satisfactory. The maximum force of the impulse wave was less than 1 acceleration of gravity (which is safe). The patients tolerated the treatment well with no significant problems related to the catheters being left in situ for up to 14 days. Conclusion: Based on this pilot experience a phase I dose escalating and morbidity study has been initiated.

Original languageEnglish (US)
Pages (from-to)247-249
Number of pages3
JournalInternational Journal of Radiation Oncology, Biology, Physics
Issue number1
StatePublished - Jan 1 1994


  • Brachytherapy
  • Glioma
  • High-dose rate
  • Stereotactic

ASJC Scopus subject areas

  • Radiation
  • Radiology Nuclear Medicine and imaging
  • Oncology


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