Purpose: To develop a catheter system for fractionated high-dose rate (HDR) brachytherapy for intracranial gliomas. Methods and Materials: The catheter system for stereotactic placement as well as delivery of the high-dose rate iridium-192 source wire is described. The force of the impulse wave from the source wire entering brain equivalent material was measured. Dose volume histograms for the first 5 patients treated are presented. Results: The catheter system was found to be satisfactory. The maximum force of the impulse wave was less than 1 acceleration of gravity (which is safe). The patients tolerated the treatment well with no significant problems related to the catheters being left in situ for up to 14 days. Conclusion: Based on this pilot experience a phase I dose escalating and morbidity study has been initiated.
|Original language||English (US)|
|Number of pages||3|
|Journal||International Journal of Radiation Oncology, Biology, Physics|
|State||Published - Jan 1 1994|
- High-dose rate
ASJC Scopus subject areas
- Radiology Nuclear Medicine and imaging