Four dimensional bolus tagging imaging of pulsatile flow

Anders Franck, Liang Der Jou, Rem Van Tyen, David Saloner

Research output: Contribution to journalArticlepeer-review

3 Scopus citations


Inversion bolus tagging MR methods were used to provide a graphic depiction of the axial velocity in three spatial dimensions for pulsatile flow through complex geometries. Visualization of the flow field was readily apparent, and a train of tagged boli were depicted providing an immediate overview of the displacement of flowing fluid over the entire pulsatile cycle. Tagging efficiency obtained using adiabatic inversion pulses was improved compared to that with a windowed sinc pulse. Results from phantom experiments on steady flow were correlated with computational fluid dynamic (CFD) simulations. The use of 3D methods reduced spatial partial volume effects, and the displacement of boli in a steady flow experiment correlated well with CFD simulations. The use of adiabatic inversion pulses resulted in sharp edged inversion regions with good retention of longitudinal magnetization. However in order to keep the pulse duration short, of the order of 2-5 ms, a rather large RF amplitude had to be used. The inversion bolus tagging method is useful in visualizing the flow field in multiple levels for pulsatile fluid flowing through complex geometries, and may be useful in fluid dynamic applications. (C) 2000 Elsevier Science Inc.

Original languageEnglish (US)
Pages (from-to)1097-1107
Number of pages11
JournalMagnetic Resonance Imaging
Issue number9
StatePublished - 2000

ASJC Scopus subject areas

  • Biophysics
  • Biomedical Engineering
  • Radiology Nuclear Medicine and imaging


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