Fluorescent labeling of human mesenchymal stem cells by thiophene fluorophores conjugated to a lipophilic carrier

Maria Duca; Barbara Dozza; Enrico Lucarelli; Spartaco Santi; Audrey Di Giorgio; Giovanna Barbarella

doi:10.1039/c0cc01918f

Fluorescent labeling of human mesenchymal stem cells by thiophene fluorophores conjugated to a lipophilic carrier

Maria Duca, Barbara Dozza, Enrico Lucarelli, Spartaco Santi, Audrey Di Giorgio, Giovanna Barbarella

Houston Methodist

Research output: Contribution to journal › Article › peer-review

20 Scopus citations

Abstract

Fluorescent labeling of human mesenchymal stem cells (hMSCs) is essential for their study in vitro and in vivo. Here, we report a new chemical biodelivery method for labeling hMSCs using a series of very efficient and highly versatile thiophene-based fluorescent dyes. Such conjugates contribute to a stable and viable labeling of hMSCs and constitute a promising strategy for in vivo applications.

Original language	English (US)
Pages (from-to)	7948-7950
Number of pages	3
Journal	Chemical Communications
Volume	46
Issue number	42
DOIs	https://doi.org/10.1039/c0cc01918f
State	Published - Nov 14 2010

ASJC Scopus subject areas

Catalysis
Electronic, Optical and Magnetic Materials
Ceramics and Composites
General Chemistry
Surfaces, Coatings and Films
Metals and Alloys
Materials Chemistry

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abstract = "Fluorescent labeling of human mesenchymal stem cells (hMSCs) is essential for their study in vitro and in vivo. Here, we report a new chemical biodelivery method for labeling hMSCs using a series of very efficient and highly versatile thiophene-based fluorescent dyes. Such conjugates contribute to a stable and viable labeling of hMSCs and constitute a promising strategy for in vivo applications.",

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AU - Duca, Maria

AU - Dozza, Barbara

AU - Lucarelli, Enrico

AU - Santi, Spartaco

AU - Di Giorgio, Audrey

AU - Barbarella, Giovanna

PY - 2010/11/14

Y1 - 2010/11/14

N2 - Fluorescent labeling of human mesenchymal stem cells (hMSCs) is essential for their study in vitro and in vivo. Here, we report a new chemical biodelivery method for labeling hMSCs using a series of very efficient and highly versatile thiophene-based fluorescent dyes. Such conjugates contribute to a stable and viable labeling of hMSCs and constitute a promising strategy for in vivo applications.

AB - Fluorescent labeling of human mesenchymal stem cells (hMSCs) is essential for their study in vitro and in vivo. Here, we report a new chemical biodelivery method for labeling hMSCs using a series of very efficient and highly versatile thiophene-based fluorescent dyes. Such conjugates contribute to a stable and viable labeling of hMSCs and constitute a promising strategy for in vivo applications.

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U2 - 10.1039/c0cc01918f

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M3 - Article

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Fluorescent labeling of human mesenchymal stem cells by thiophene fluorophores conjugated to a lipophilic carrier

Abstract

ASJC Scopus subject areas

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