Five new iridoids from Patrinia rupestris

Xiu Ping Yang, Er Wei Li, Qi Zhang, Cheng Shan Yuan, Zhong Jian Jia

Research output: Contribution to journalArticlepeer-review

45 Scopus citations


Five new iridoids, namely rupesin A-E (1-5, resp.), together with six known iridoids, 6-11, were isolated from the roots of Patrinia rupestris. Their structures were elucidated by spectroscopic methods including IR, UV, MS, and 1D- and 2D-NMR experiments, and comparison with data of known analogues. Compounds 4 and 11, compounds 1, 2, 5, 6, 8, 9, and 10, and compounds 3, 4, and 8 showed significant antibacterial activities against Bacillus subtilis, Escherichia coli, and Staphylococcus aureus, respectively.

Original languageEnglish (US)
Pages (from-to)762-770
Number of pages9
JournalChemistry and Biodiversity
Issue number7
StatePublished - 2006

ASJC Scopus subject areas

  • Bioengineering
  • Biochemistry
  • Chemistry(all)
  • Molecular Medicine
  • Molecular Biology


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