First-in-human experience of an antidote-controlled anticoagulant using RNA aptamer technology: A phase 1a pharmacodynamic evaluation of a drug-antidote pair for the controlled regulation of factor IXa activity

Christopher K. Dyke, Steven R. Steinhubl, Neal S. Kleiman, Richard O. Cannon, Laura G. Aberle, Min Lin, Shelley K. Myles, Chiara Melloni, Robert A. Harrington, John H. Alexander, Richard C. Becker, Christopher P. Rusconi

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189 Scopus citations

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Medicine & Life Sciences