TY - JOUR
T1 - Fine-needle aspiration cytology of a case of oncocytic adrenocortical carcinoma
AU - Krishnamurthy, Savitri
AU - Ordóñez, Nelson G.
AU - Shelton, Thomas O.
AU - Ayala, Alberto G.
AU - Sneige, Nour
PY - 2000/5
Y1 - 2000/5
N2 - We report on the results of fine-needle aspiration cytology of a case of oncocytic adrenocortical carcinoma in a 39-yr-old man. The tumor invaded the inferior vena cava and extended up to the right atrium. Aspirate smears were very cellular and showed a monomorphic population of large polyhedral cells with abundant granular cytoplasm, predominantly distributed singly. Mitotic activity was inconspicuous, and there was no necrosis. Immunohistochemically, the tumor cells were positive for vimentin, cytokeratin, and p53, and negative for synaptophysin, chromogranin, inhibin, and S-100. Ultrastructurally, the cytoplasm of the tumor cells was packed with mitochondria. The patient underwent left radical nephrectomy as well as a combined cardiopulmonary bypass, with atriotomy and resection of the tumor from the right atrium and inferior vena cava. Three months of postoperative follow-up were uneventful. (C) 2000 Wiley-Liss, Inc.
AB - We report on the results of fine-needle aspiration cytology of a case of oncocytic adrenocortical carcinoma in a 39-yr-old man. The tumor invaded the inferior vena cava and extended up to the right atrium. Aspirate smears were very cellular and showed a monomorphic population of large polyhedral cells with abundant granular cytoplasm, predominantly distributed singly. Mitotic activity was inconspicuous, and there was no necrosis. Immunohistochemically, the tumor cells were positive for vimentin, cytokeratin, and p53, and negative for synaptophysin, chromogranin, inhibin, and S-100. Ultrastructurally, the cytoplasm of the tumor cells was packed with mitochondria. The patient underwent left radical nephrectomy as well as a combined cardiopulmonary bypass, with atriotomy and resection of the tumor from the right atrium and inferior vena cava. Three months of postoperative follow-up were uneventful. (C) 2000 Wiley-Liss, Inc.
KW - Adrenal gland
KW - Adrenocortical tumor
KW - Aspiration cytology
KW - Oncocytic tumor
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U2 - 10.1002/(SICI)1097-0339(200005)22:5<299::AID-DC8>3.0.CO;2-5
DO - 10.1002/(SICI)1097-0339(200005)22:5<299::AID-DC8>3.0.CO;2-5
M3 - Article
C2 - 10790237
AN - SCOPUS:18144439841
SN - 8755-1039
VL - 22
SP - 299
EP - 303
JO - Diagnostic Cytopathology
JF - Diagnostic Cytopathology
IS - 5
ER -