Fibrous Dysplasia of the Sphenoid and Skull Base

Moran Amit, Dan M. Fliss, Ziv Gil

Research output: Contribution to journalReview articlepeer-review

26 Scopus citations


This article reviews the current literature and level-1 evidence of the natural history and the medical and surgical treatment of skull base fibrous dysplasia. The high rate of optic nerve (ON) involvement and the potential risk of visual impairment as a result of nerve compression have led many surgeons to suggest prophylactic decompression of the ON in asymptomatic patients. However, review of the cases reported in the literature reveals that ON decompression surgery is indicated only for patients with visual deficits, whereas asymptomatic patients with radiologic evidence of ON compression are better managed conservatively.

Original languageEnglish (US)
Pages (from-to)891-902
Number of pages12
JournalOtolaryngologic Clinics of North America
Issue number4
StatePublished - Aug 2011


  • Decompression
  • Fibrous dysplasia
  • Natural history
  • Skull base
  • Sphenoid

ASJC Scopus subject areas

  • Otorhinolaryngology


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