TY - JOUR
T1 - Fibrosarcoma of the head and neck
AU - Frankenthaler, Robert
AU - Ayala, Alberto G.
AU - Hartwick, R. Warren
AU - Goepfert, Helmuth
PY - 1990/8
Y1 - 1990/8
N2 - A review of 118 archival cases originally diagnosed as fibrosarcoma of the head and neck is presented. Sites of involvement were the sinonasal region, upper aerodigestive tract, skin, and soft tissues. Review of the pathologic specimens applying strict histopathologic criteria including immunohistochemical techniques reclassified many of the tumors as malignant fibrous histiocytoma, monophasic synovial sarcoma-like neoplasm, or dermatofibrosarcoma protuberans. Improved clinical outcome correlated significantly with lesser tumor size, lower histologic grade, and negative surgical margins. Location in the skin or soft tissue tended to convey improved survival, although not to a level of statistical significance.
AB - A review of 118 archival cases originally diagnosed as fibrosarcoma of the head and neck is presented. Sites of involvement were the sinonasal region, upper aerodigestive tract, skin, and soft tissues. Review of the pathologic specimens applying strict histopathologic criteria including immunohistochemical techniques reclassified many of the tumors as malignant fibrous histiocytoma, monophasic synovial sarcoma-like neoplasm, or dermatofibrosarcoma protuberans. Improved clinical outcome correlated significantly with lesser tumor size, lower histologic grade, and negative surgical margins. Location in the skin or soft tissue tended to convey improved survival, although not to a level of statistical significance.
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U2 - 10.1288/00005537-199008000-00001
DO - 10.1288/00005537-199008000-00001
M3 - Article
C2 - 2166190
AN - SCOPUS:0025073599
SN - 0023-852X
VL - 100
SP - 799
EP - 802
JO - Laryngoscope
JF - Laryngoscope
IS - 8
ER -