Fibrosarcoma of the head and neck

Robert Frankenthaler, Alberto G. Ayala, R. Warren Hartwick, Helmuth Goepfert

Research output: Contribution to journalArticlepeer-review

38 Scopus citations


A review of 118 archival cases originally diagnosed as fibrosarcoma of the head and neck is presented. Sites of involvement were the sinonasal region, upper aerodigestive tract, skin, and soft tissues. Review of the pathologic specimens applying strict histopathologic criteria including immunohistochemical techniques reclassified many of the tumors as malignant fibrous histiocytoma, monophasic synovial sarcoma-like neoplasm, or dermatofibrosarcoma protuberans. Improved clinical outcome correlated significantly with lesser tumor size, lower histologic grade, and negative surgical margins. Location in the skin or soft tissue tended to convey improved survival, although not to a level of statistical significance.

Original languageEnglish (US)
Pages (from-to)799-802
Number of pages4
Issue number8
StatePublished - Aug 1990

ASJC Scopus subject areas

  • Otorhinolaryngology


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