Fibronectin-α4β1 interactions in hepatic cold ischemia and reperfusion injury: Regulation of MMP-9 and MT1-MMP via the p38 MAPK pathway

Keyphrases

• Ischemia-reperfusion Injury 100%
• Fibronectin 100%
• Matrix metalloproteinase-9 (MMP-9) 100%
• Cold Ischemia Injury 100%
• MT1-MMP 100%
• P38 MAPK Pathway 100%
• P38 Mitogen-activated Protein Kinase (p38 MAPK) 50%
• MMP14 50%
• Macrophages 37%
• Liver Ischemia-reperfusion Injury 37%
• Mitogen-activated Protein Kinase 25%
• Kinase Cascade 25%
• Peptide Drugs 25%
• Hepatic Ischemia-reperfusion Injury 25%
• Endothelial Cells 12%
• Cyclooxygenase-2 12%
• Liver Injury 12%
• Integrin 12%
• Inflammatory Mediators 12%
• Response to Injury 12%
• Inducible Nitric Oxide Synthase 12%
• Phosphorylation 12%
• Proteolysis 12%
• Clinical Setting 12%
• Recipient Survival 12%
• Leukocytes 12%
• Pathway Control 12%
• Inflammatory Process 12%
• SB203580 12%
• Challenging Problems 12%
• Prominent Features 12%
• Pharmacological Strategies 12%
• Leukocyte Recruitment 12%
• Local Release 12%
• Hepatic Response 12%

Pharmacology, Toxicology and Pharmaceutical Science

• Ischemia 100%
• Reperfusion Injury 100%
• Fibronectin 100%
• Gelatinase B 100%
• Matrix Metalloproteinase 14 100%
• Liver Ischemia 50%
• Phosphotransferase 20%
• Inflammation 10%
• Liver Injury 10%
• Tumor Necrosis Factor 10%
• Survival Rate 10%
• Integrin 10%
• Cyclic AMP Dependent Protein Kinase 10%
• SB 203580 10%

Immunology and Microbiology

• Reperfusion 100%
• Fibronectin 100%
• Cold Ischemia 100%
• Macrophage 37%
• Peptides 37%
• Tumor Necrosis Factor 12%
• Leukocyte 12%
• Integrin 12%
• Mediator 12%
• Protein Degradation 12%
• Survival Rate 12%
• Leukocyte Recruitment 12%