TY - JOUR
T1 - Female reproductive organ-sparing radical cystectomy
T2 - Contemporary indications, techniques and outcomes
AU - Niver, Ben E.
AU - Daneshmand, Siamak
AU - Satkunasivam, Raj
PY - 2015/1/1
Y1 - 2015/1/1
N2 - Surgical techniques to spare female reproductive organs at the time of radical cystectomy [reproductive organ-sparing radical cystectomy (ROSRC)] have been advocated to improve quality of life with respect to sexual and urinary function. These potential benefits must be weighed against the risk of inappropriate patient selection and related oncologic risk. RECENT FINDINGS: In this review, we describe the evidence to define the appropriate selection criteria to minimize clinical understaging. The literature provides small cohorts with intermediate-term follow-up to support oncologic safety, and thus ROSRC must continue to be evaluated with long-term studies. Pertinent techniques for ROSRC are described based on underlying anatomic principles. Lastly, studies on the potential sexual and urinary functional advantages are promising, but must be evaluated in light of the excellent baseline functional characteristics of those selected for inclusion. SUMMARY: ROSRC appears to provide measurable benefits to sexual and urinary function. However, the magnitude of these benefits is unclear and the selection of appropriate candidates requires further prospective study vis-a-vis oncologic control. ROSRC must be adopted cautiously until further data are available.
AB - Surgical techniques to spare female reproductive organs at the time of radical cystectomy [reproductive organ-sparing radical cystectomy (ROSRC)] have been advocated to improve quality of life with respect to sexual and urinary function. These potential benefits must be weighed against the risk of inappropriate patient selection and related oncologic risk. RECENT FINDINGS: In this review, we describe the evidence to define the appropriate selection criteria to minimize clinical understaging. The literature provides small cohorts with intermediate-term follow-up to support oncologic safety, and thus ROSRC must continue to be evaluated with long-term studies. Pertinent techniques for ROSRC are described based on underlying anatomic principles. Lastly, studies on the potential sexual and urinary functional advantages are promising, but must be evaluated in light of the excellent baseline functional characteristics of those selected for inclusion. SUMMARY: ROSRC appears to provide measurable benefits to sexual and urinary function. However, the magnitude of these benefits is unclear and the selection of appropriate candidates requires further prospective study vis-a-vis oncologic control. ROSRC must be adopted cautiously until further data are available.
KW - Female organ sparing
KW - radical cystectomy
KW - reproductive organ sparing
KW - urothelial cancer
UR - http://www.scopus.com/inward/record.url?scp=84922407310&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84922407310&partnerID=8YFLogxK
U2 - 10.1097/MOU.0000000000000146
DO - 10.1097/MOU.0000000000000146
M3 - Review article
C2 - 25581538
AN - SCOPUS:84922407310
SN - 0963-0643
VL - 25
SP - 105
EP - 110
JO - Current Opinion in Urology
JF - Current Opinion in Urology
IS - 2
ER -