TY - JOUR
T1 - Feasibility and Efficacy of Low-profile Visual Intraluminal Support Device
T2 - A Single Center Five-year Experience
AU - Davidov, Vitaliy
AU - Sadrameli, Saeed
AU - Desai, Virendra
AU - Lee, Jonathan
AU - Austerman, Ryan
AU - Jenson, Amanda
AU - Boghani, Zain
AU - Britz, Gavin
AU - Diaz, Orlando
AU - Klucznik, Richard P.
AU - Zhang, Yi Jonathan
N1 - Publisher Copyright:
© 2021 Bentham Science Publishers.
PY - 2021/6
Y1 - 2021/6
N2 - Introduction: The Low-Profile Visualized Intraluminal Support (LVIS) devices are a new generation of self-expandable, high-porosity stents approved for the treatment of large to giant wide-necked intracranial aneurysms via stent-assisted coiling. Here we report the radiographic and clinical outcomes seen with LVIS, LVIS Jr. and LVIS Blue from a single institution over a fiveyear period. Methods: Patients with intracranial aneurysms treated by LVIS, LVIS Jr. and LVIS Blue technology over a five-year period (2012-2017) at our institution were retrospectively reviewed. Results: Seventy-four patients (55 females and 19 males; average age = 59.2) with 74 aneurysms underwent embolization of intracranial aneurysms using LVIS (N = 10), LVIS Jr. (N = 47) or LVIS Blue (N = 12) devices at our institution over the study period. The most common location of treated aneurysms was the anterior communicating artery (31%), followed by the basilar artery (19%), and the middle cerebral artery (13%). The mean neck and dome sizes were 3.9±1.5mm and 6.6±3.2mm, respectively. The median follow-up time was 6 months. At the last radiographic follow-up, 93.1% of patients had complete occlusion (RR-I or OKM-D). In 5 cases (7%), the LVIS stent failed to open, requiring balloon angioplasty (N = 3) or stent recapture and use of a non-LVIS branded device (N = 2). Five patients had post-embolization infarcts, and 1 patient had an intra-operative dome rupture. Conclusion: LVIS brand of stents is a safe, effective, and technically feasible treatment strategy for wide-neck intracranial aneurysms, with high deployment success and aneurysm obliteration rates.
AB - Introduction: The Low-Profile Visualized Intraluminal Support (LVIS) devices are a new generation of self-expandable, high-porosity stents approved for the treatment of large to giant wide-necked intracranial aneurysms via stent-assisted coiling. Here we report the radiographic and clinical outcomes seen with LVIS, LVIS Jr. and LVIS Blue from a single institution over a fiveyear period. Methods: Patients with intracranial aneurysms treated by LVIS, LVIS Jr. and LVIS Blue technology over a five-year period (2012-2017) at our institution were retrospectively reviewed. Results: Seventy-four patients (55 females and 19 males; average age = 59.2) with 74 aneurysms underwent embolization of intracranial aneurysms using LVIS (N = 10), LVIS Jr. (N = 47) or LVIS Blue (N = 12) devices at our institution over the study period. The most common location of treated aneurysms was the anterior communicating artery (31%), followed by the basilar artery (19%), and the middle cerebral artery (13%). The mean neck and dome sizes were 3.9±1.5mm and 6.6±3.2mm, respectively. The median follow-up time was 6 months. At the last radiographic follow-up, 93.1% of patients had complete occlusion (RR-I or OKM-D). In 5 cases (7%), the LVIS stent failed to open, requiring balloon angioplasty (N = 3) or stent recapture and use of a non-LVIS branded device (N = 2). Five patients had post-embolization infarcts, and 1 patient had an intra-operative dome rupture. Conclusion: LVIS brand of stents is a safe, effective, and technically feasible treatment strategy for wide-neck intracranial aneurysms, with high deployment success and aneurysm obliteration rates.
KW - Aneurysm
KW - Device
KW - Endovascular
KW - LVIS devices
KW - Stroke
KW - Subarachnoid
UR - http://www.scopus.com/inward/record.url?scp=85123388221&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=85123388221&partnerID=8YFLogxK
U2 - 10.2174/1567202618666210910123134
DO - 10.2174/1567202618666210910123134
M3 - Article
C2 - 34515001
AN - SCOPUS:85123388221
SN - 1567-2026
VL - 18
SP - 279
EP - 286
JO - Current Neurovascular Research
JF - Current Neurovascular Research
IS - 3
ER -