Fatal cerebral venous thrombosis as the initial manifestation of the antiphospholipid syndrome

Ramtin Agah, Lawrence Rice, John Winikates

Research output: Contribution to journalArticlepeer-review

9 Scopus citations

Abstract

We describe a patient with cerebral venous thrombosis (CVT) who presented with thrombocytopenia and persistent headache. The etiology of her CVT was determined to be the antiphospholipid syndrome (APLS) based on a prolonged dilute Russell viper venom test and elevated anti-cardiolipin IgG antibody. CVT has rarely been reported as the initial manifestation of the APLS. Despite supportive measures and anticoagulation, the patient expired. Clinicians should consider the possibility of CVT when coagulation abnormalities consistent with APLS are combined with neurologic symptoms. Early detection and treatment are crucial for a favorable outcome.

Original languageEnglish (US)
Pages (from-to)189-191
Number of pages3
JournalClinical Neurology and Neurosurgery
Volume98
Issue number2
DOIs
StatePublished - Jan 1 1996

Keywords

  • Anti-phospholipid antibody
  • Cerebral venous thrombosis
  • Venous stroke

ASJC Scopus subject areas

  • Clinical Neurology
  • Surgery
  • Neurology

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