TY - JOUR
T1 - Fatal cerebral venous thrombosis as the initial manifestation of the antiphospholipid syndrome
AU - Agah, Ramtin
AU - Rice, Lawrence
AU - Winikates, John
PY - 1996/1/1
Y1 - 1996/1/1
N2 - We describe a patient with cerebral venous thrombosis (CVT) who presented with thrombocytopenia and persistent headache. The etiology of her CVT was determined to be the antiphospholipid syndrome (APLS) based on a prolonged dilute Russell viper venom test and elevated anti-cardiolipin IgG antibody. CVT has rarely been reported as the initial manifestation of the APLS. Despite supportive measures and anticoagulation, the patient expired. Clinicians should consider the possibility of CVT when coagulation abnormalities consistent with APLS are combined with neurologic symptoms. Early detection and treatment are crucial for a favorable outcome.
AB - We describe a patient with cerebral venous thrombosis (CVT) who presented with thrombocytopenia and persistent headache. The etiology of her CVT was determined to be the antiphospholipid syndrome (APLS) based on a prolonged dilute Russell viper venom test and elevated anti-cardiolipin IgG antibody. CVT has rarely been reported as the initial manifestation of the APLS. Despite supportive measures and anticoagulation, the patient expired. Clinicians should consider the possibility of CVT when coagulation abnormalities consistent with APLS are combined with neurologic symptoms. Early detection and treatment are crucial for a favorable outcome.
KW - Anti-phospholipid antibody
KW - Cerebral venous thrombosis
KW - Venous stroke
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U2 - 10.1016/0303-8467(96)00006-6
DO - 10.1016/0303-8467(96)00006-6
M3 - Article
C2 - 8836598
AN - SCOPUS:0030152949
VL - 98
SP - 189
EP - 191
JO - Clinical Neurology and Neurosurgery
JF - Clinical Neurology and Neurosurgery
SN - 0303-8467
IS - 2
ER -