TY - JOUR
T1 - Fast-field-echo MR imaging with Gd-DTPA
T2 - Physiologic evaluation of the kidney and liver
AU - Pettigrew, Roderic I.
AU - Avruch, L.
AU - Dannels, W.
AU - Coumans, J.
AU - Bernardino, M. E.
PY - 1986/1/1
Y1 - 1986/1/1
N2 - To determine if magnetic resonance imaging with Gd-DTPA could be used to assess renal and hepatic perfusion and possibly function, a fast-field-echo technique was used to perform sequential imaging of the kidney and liver of five subjects. Sixteen 3-second images of the same section were obtained at 13-second intervals immediately after Gd-DTPA administration, and again at 30 or 50 minutes after injection. From these images, curves of renal and hepatic signal versus time were generated. In each case the renal signal intensity peaked within 2 minutes and decreased to 60% or less by 3.4 minutes, and 35% or less by 50 minutes. Hepatic curves peaked within 2 minutes and approached initial levels by 30 minutes. These results suggest that transit and clearance of the contrast agent can be imaged by this technique.
AB - To determine if magnetic resonance imaging with Gd-DTPA could be used to assess renal and hepatic perfusion and possibly function, a fast-field-echo technique was used to perform sequential imaging of the kidney and liver of five subjects. Sixteen 3-second images of the same section were obtained at 13-second intervals immediately after Gd-DTPA administration, and again at 30 or 50 minutes after injection. From these images, curves of renal and hepatic signal versus time were generated. In each case the renal signal intensity peaked within 2 minutes and decreased to 60% or less by 3.4 minutes, and 35% or less by 50 minutes. Hepatic curves peaked within 2 minutes and approached initial levels by 30 minutes. These results suggest that transit and clearance of the contrast agent can be imaged by this technique.
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U2 - 10.1148/radiology.160.2.3726139
DO - 10.1148/radiology.160.2.3726139
M3 - Article
C2 - 3726139
AN - SCOPUS:0022454810
VL - 160
SP - 561
EP - 563
JO - Radiology
JF - Radiology
SN - 0033-8419
IS - 2
ER -