A case of familial vesicoureteral reflux occurring in a mother and daughter is presented. A review of the literature reveals 85 previous cases. Although the hereditary incidence of this abnormality has been overlooked in the past, it may be as high as 20 per cent. Careful analysis of families of patients with reflux is strongly advocated. Guidelines for investigation are set forth in order to find cases of silent reflux and to avoid the dangers of progressive renal damage.
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