False-positive lesions mimicking breast cancer on FDG PET and PET/CT

Margaret Adejolu; Lei Huo; Eric M. Rohren; Lumarie Santiago; Wei T. Yang

doi:10.2214/AJR.11.7130

False-positive lesions mimicking breast cancer on FDG PET and PET/CT

Margaret Adejolu, Lei Huo, Eric M. Rohren, Lumarie Santiago, Wei T. Yang

Houston Methodist

Research output: Contribution to journal › Review article › peer-review

114 Scopus citations

Abstract

OBJECTIVE. Incidental ¹⁸F-FDG-avid breast lesions are commonly encountered in patients with cancer who undergo staging PET/CT. This pictorial essay discusses breast lesions that show increased FDG activity, mimicking breast cancer, with biopsy-confirmed benign diagnosis. CONCLUSION. Acute and chronic inflammation, physiologic lactation, and benign breast masses, including silicone granuloma, fat necrosis, fibroadenoma, and postsurgical changes, may show increased FDG uptake on PET/CT. These conditions can often be differentiated from malignancy by correlative imaging, including mammography, sonography, or MRI.

Original language	English (US)
Journal	American Journal of Roentgenology
Volume	198
Issue number	3
DOIs	https://doi.org/10.2214/AJR.11.7130
State	Published - Mar 1 2012

Keywords

Breast
Mammography
Neoplasm
PET/CT
Ultrasound

ASJC Scopus subject areas

Radiology Nuclear Medicine and imaging

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10.2214/AJR.11.7130

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title = "False-positive lesions mimicking breast cancer on FDG PET and PET/CT",

abstract = "OBJECTIVE. Incidental 18F-FDG-avid breast lesions are commonly encountered in patients with cancer who undergo staging PET/CT. This pictorial essay discusses breast lesions that show increased FDG activity, mimicking breast cancer, with biopsy-confirmed benign diagnosis. CONCLUSION. Acute and chronic inflammation, physiologic lactation, and benign breast masses, including silicone granuloma, fat necrosis, fibroadenoma, and postsurgical changes, may show increased FDG uptake on PET/CT. These conditions can often be differentiated from malignancy by correlative imaging, including mammography, sonography, or MRI.",

keywords = "Breast, Mammography, Neoplasm, PET/CT, Ultrasound",

author = "Margaret Adejolu and Lei Huo and Rohren, \{Eric M.\} and Lumarie Santiago and Yang, \{Wei T.\}",

year = "2012",

month = mar,

day = "1",

doi = "10.2214/AJR.11.7130",

language = "English (US)",

volume = "198",

journal = "American Journal of Roentgenology",

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TY - JOUR

T1 - False-positive lesions mimicking breast cancer on FDG PET and PET/CT

AU - Adejolu, Margaret

AU - Huo, Lei

AU - Rohren, Eric M.

AU - Santiago, Lumarie

AU - Yang, Wei T.

PY - 2012/3/1

Y1 - 2012/3/1

N2 - OBJECTIVE. Incidental 18F-FDG-avid breast lesions are commonly encountered in patients with cancer who undergo staging PET/CT. This pictorial essay discusses breast lesions that show increased FDG activity, mimicking breast cancer, with biopsy-confirmed benign diagnosis. CONCLUSION. Acute and chronic inflammation, physiologic lactation, and benign breast masses, including silicone granuloma, fat necrosis, fibroadenoma, and postsurgical changes, may show increased FDG uptake on PET/CT. These conditions can often be differentiated from malignancy by correlative imaging, including mammography, sonography, or MRI.

AB - OBJECTIVE. Incidental 18F-FDG-avid breast lesions are commonly encountered in patients with cancer who undergo staging PET/CT. This pictorial essay discusses breast lesions that show increased FDG activity, mimicking breast cancer, with biopsy-confirmed benign diagnosis. CONCLUSION. Acute and chronic inflammation, physiologic lactation, and benign breast masses, including silicone granuloma, fat necrosis, fibroadenoma, and postsurgical changes, may show increased FDG uptake on PET/CT. These conditions can often be differentiated from malignancy by correlative imaging, including mammography, sonography, or MRI.

KW - Breast

KW - Mammography

KW - Neoplasm

KW - PET/CT

KW - Ultrasound

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DO - 10.2214/AJR.11.7130

M3 - Review article

C2 - 22358030

AN - SCOPUS:84863274620

SN - 0361-803X

VL - 198

JO - American Journal of Roentgenology

JF - American Journal of Roentgenology

IS - 3

ER -

False-positive lesions mimicking breast cancer on FDG PET and PET/CT

Abstract

Keywords

ASJC Scopus subject areas

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