Abstract
Prophylactic treatment of couples with oral penicillin has been recommended as a means of eradicating GBS from the parturient female. In 1977 and 1978 this hypothesis was tested in an investigation of couples from a middle and upper socioeconomic group in Houston, Texas. A group of 40 women, known to be colonized with GBS during the third trimester of pregnancy, and their husbands were treated simultaneously with oral penicillin. Patients were recultured 3 weeks following completion of therapy and at the time of delivery. At the time of delivery 67% of the women remained colonized with GBS. This percentage does not differ substantially from that obtained in a series of untreated colonized women. This study demonstrates that oral penicillin treatment of couples is not an effective means of reducing maternal colonization at the time of delivery.
Original language | English (US) |
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Pages (from-to) | 1062-1065 |
Number of pages | 4 |
Journal | American Journal of Obstetrics and Gynecology |
Volume | 135 |
Issue number | 8 |
DOIs | |
State | Published - Dec 15 1979 |
ASJC Scopus subject areas
- Obstetrics and Gynecology