Factors in the technical quality of gadolinium enhanced magnetic resonance angiography for pulmonary embolism in PIOPED III

H. Dirk Sostman, Kathleen A. Jablonski, Pamela K. Woodard, Paul D. Stein, David P. Naidich, Thomas L. Chenevert, John G. Weg, Charles A. Hales, Russell D. Hull, Lawrence R. Goodman, Victor F. Tapson

Research output: Contribution to journalArticle

16 Scopus citations

Abstract

In a multi-center trial, gadolinium enhanced magnetic resonance angiography (MRA) for diagnosis of acute pulmonary embolism (PE) had a high rate of technically inadequate images. Accordingly, we evaluated the reasons for poor quality MRA of the pulmonary arteries in these patients. We performed a retrospective analysis of the data collected in the PIOPED III study. We assessed the relationship to the proportion of examinations deemed "uninterpretable"by central readers to the clinical centers, MR equipment platform and vendors, degree of vascular opacification in different orders of pulmonary arteries; type, frequency and severity of image artifacts; patient co-morbidities, symptoms and signs; and reader characteristics. Centers, MR equipment vendor and platform, degree of vascular opacification, and motion artifacts influenced the likelihood of central reader determinations that images were "uninterpretable". Neither the reader nor patient characteristics (age, body mass index, respiratory rate, heart rate) correlated with the likelihood of determining examinations "uninterpretable". Vascular opacification and motion artifact are the principal factors influencing MRA interpretability. Some centers obtain better images more consistently, but the reasons for differences between centers are unclear.

Original languageEnglish (US)
Pages (from-to)303-312
Number of pages10
JournalInternational Journal of Cardiovascular Imaging
Volume28
Issue number2
DOIs
StatePublished - Feb 2012

Keywords

  • Artifacts
  • Image quality
  • Pulmonary embolism
  • Pulmonary MR angiography

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging
  • Cardiology and Cardiovascular Medicine

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