Factors and outcomes associated with surgical treatment options of contralateral breast cancer

Amanda K. Arrington, Amy Voci, Laura Reparaz, William Fry

Research output: Contribution to journalArticlepeer-review

6 Scopus citations


Methods: The Surveillance, Epidemiology, and End Results (SEER) cancer database was queried to identify CBC patients from 1998 to 2010. Relevant data were compared among the surgical treatment groups of lumpectomy, mastectomy, and mastectomy/reconstruction

Results: Of 1,534 patients, 31% underwent lumpectomy and 69% underwent mastectomy [201 (21%) mastectomy/reconstruction; 748 (69%) mastectomy alone]. Older patients (age >80 years) were more likely to undergo lumpectomy; those with larger tumors (T4) or node-positive disease more often underwent mastectomy. Overall survival was significantly higher in the mastectomy/reconstruction group (P =.05)

Conclusions: Younger age, larger tumor size, and positive nodal disease were independently associated with mastectomy. As the number of long-term breast cancer survivors increases, factors contributing to CBC treatments must be studied to maximize survival potential.

Background The treatment for a contralateral breast cancer (CBC) presents a growing dilemma given the expanding number of long-term survivors. We hypothesize that there will be specific surgical treatment trends with demographic differences between the treatment groups

Original languageEnglish (US)
Pages (from-to)524-530
Number of pages7
JournalAmerican Journal of Surgery
Issue number4
StatePublished - Oct 1 2014


  • cancer
  • Contralateral breast
  • Second breast cancer
  • Surgical treatments

ASJC Scopus subject areas

  • Surgery


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