TY - JOUR
T1 - Extreme hypercholesterolemia in cholestatic sarcoidosis due to lipoprotein X
T2 - Exploring the cholesterol gap
AU - Yehya, Ahmad
AU - Huang, Rongrong
AU - Bernard, David W.
AU - Gotto, Antonio
AU - Robbins, Richard J.
N1 - Publisher Copyright:
© 2018 The Authors
Copyright:
Copyright 2018 Elsevier B.V., All rights reserved.
PY - 2018/12
Y1 - 2018/12
N2 - Lipoprotein-X (LpX) is a rare lipid particle that can affect lipid analysis and interpretation. Case reports of LpX syndrome have been described scarcely. LpX has been linked to diseases associated with cholangiopathy and thus, in such instances, hyperlipidemia can be falsely attributed to an elevated LDL-cholesterol component or to an unknown lipid moiety. The management of LpX syndrome is completely different than that of classic hypercholesterolemia. This article describes a case of LpX syndrome and provides a review of similar cases in the literature. This review also discusses the technical measurement of LpX, management expectations and sequelae of the disease.
AB - Lipoprotein-X (LpX) is a rare lipid particle that can affect lipid analysis and interpretation. Case reports of LpX syndrome have been described scarcely. LpX has been linked to diseases associated with cholangiopathy and thus, in such instances, hyperlipidemia can be falsely attributed to an elevated LDL-cholesterol component or to an unknown lipid moiety. The management of LpX syndrome is completely different than that of classic hypercholesterolemia. This article describes a case of LpX syndrome and provides a review of similar cases in the literature. This review also discusses the technical measurement of LpX, management expectations and sequelae of the disease.
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U2 - 10.1016/j.jecr.2018.08.002
DO - 10.1016/j.jecr.2018.08.002
M3 - Article
AN - SCOPUS:85052745800
SN - 2214-6245
VL - 10
SP - 11
EP - 13
JO - Journal of Clinical and Translational Endocrinology: Case Reports
JF - Journal of Clinical and Translational Endocrinology: Case Reports
ER -