Extracellular vesicle lipids in cancer immunoevasion

Siyu Chen; Dalila Iannotta; Megan L. O'Mara; Jenifer Pendiuk Goncalves; Joy Wolfram

doi:10.1016/j.trecan.2023.08.006

Extracellular vesicle lipids in cancer immunoevasion

Siyu Chen, Dalila Iannotta, Megan L. O'Mara, Jenifer Pendiuk Goncalves, Joy Wolfram

Houston Methodist

Research output: Contribution to journal › Short survey › peer-review

10 Scopus citations

Abstract

Recent studies have revealed that cancer cell-derived extracellular vesicles (EVs) modulate immunological responses. Lipids have diverse biological functions, and are known to promote tumor malignancy. However, the immunoevasive roles of EV lipids in cancer progression remain poorly understood. Nevertheless, the study of cancer cell-derived EV lipids holds great promise for diagnostic and therapeutic interventions.

Original language	English (US)
Pages (from-to)	883-886
Number of pages	4
Journal	Trends in Cancer
Volume	9
Issue number	11
DOIs	https://doi.org/10.1016/j.trecan.2023.08.006
State	Published - Nov 2023

Keywords

exosome
immunosuppression
lipidomics
microvesicle
oncology

ASJC Scopus subject areas

Oncology
Cancer Research

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10.1016/j.trecan.2023.08.006

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title = "Extracellular vesicle lipids in cancer immunoevasion",

abstract = "Recent studies have revealed that cancer cell-derived extracellular vesicles (EVs) modulate immunological responses. Lipids have diverse biological functions, and are known to promote tumor malignancy. However, the immunoevasive roles of EV lipids in cancer progression remain poorly understood. Nevertheless, the study of cancer cell-derived EV lipids holds great promise for diagnostic and therapeutic interventions.",

keywords = "exosome, immunosuppression, lipidomics, microvesicle, oncology",

author = "Siyu Chen and Dalila Iannotta and O'Mara, {Megan L.} and Goncalves, {Jenifer Pendiuk} and Joy Wolfram",

note = "Publisher Copyright: {\textcopyright} 2023 Elsevier Inc.",

year = "2023",

month = nov,

doi = "10.1016/j.trecan.2023.08.006",

language = "English (US)",

volume = "9",

pages = "883--886",

journal = "Trends in Cancer",

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T1 - Extracellular vesicle lipids in cancer immunoevasion

AU - Chen, Siyu

AU - Iannotta, Dalila

AU - O'Mara, Megan L.

AU - Goncalves, Jenifer Pendiuk

AU - Wolfram, Joy

PY - 2023/11

Y1 - 2023/11

N2 - Recent studies have revealed that cancer cell-derived extracellular vesicles (EVs) modulate immunological responses. Lipids have diverse biological functions, and are known to promote tumor malignancy. However, the immunoevasive roles of EV lipids in cancer progression remain poorly understood. Nevertheless, the study of cancer cell-derived EV lipids holds great promise for diagnostic and therapeutic interventions.

AB - Recent studies have revealed that cancer cell-derived extracellular vesicles (EVs) modulate immunological responses. Lipids have diverse biological functions, and are known to promote tumor malignancy. However, the immunoevasive roles of EV lipids in cancer progression remain poorly understood. Nevertheless, the study of cancer cell-derived EV lipids holds great promise for diagnostic and therapeutic interventions.

KW - exosome

KW - immunosuppression

KW - lipidomics

KW - microvesicle

KW - oncology

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U2 - 10.1016/j.trecan.2023.08.006

DO - 10.1016/j.trecan.2023.08.006

M3 - Short survey

C2 - 37666676

AN - SCOPUS:85169511041

SN - 2405-8033

VL - 9

SP - 883

EP - 886

JO - Trends in Cancer

JF - Trends in Cancer

IS - 11

ER -

Extracellular vesicle lipids in cancer immunoevasion

Abstract

Keywords

ASJC Scopus subject areas

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