Extracellular vesicle lipids in cancer immunoevasion

Siyu Chen, Dalila Iannotta, Megan L. O'Mara, Jenifer Pendiuk Goncalves, Joy Wolfram

Research output: Contribution to journalShort surveypeer-review

8 Scopus citations

Abstract

Recent studies have revealed that cancer cell-derived extracellular vesicles (EVs) modulate immunological responses. Lipids have diverse biological functions, and are known to promote tumor malignancy. However, the immunoevasive roles of EV lipids in cancer progression remain poorly understood. Nevertheless, the study of cancer cell-derived EV lipids holds great promise for diagnostic and therapeutic interventions.

Original languageEnglish (US)
Pages (from-to)883-886
Number of pages4
JournalTrends in Cancer
Volume9
Issue number11
DOIs
StatePublished - Nov 2023

Keywords

  • exosome
  • immunosuppression
  • lipidomics
  • microvesicle
  • oncology

ASJC Scopus subject areas

  • Oncology
  • Cancer Research

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