TY - JOUR
T1 - Exposure-based cognitive-behavioral treatment of PTSD in adults with schizophrenia or schizoaffective disorder
T2 - A pilot study
AU - Christopher Frueh, B.
AU - Grubaugh, Anouk L.
AU - Cusack, Karen J.
AU - Kimble, Matthew O.
AU - Elhai, Jon D.
AU - Knapp, Rebecca G.
N1 - Funding Information:
This work was partially supported by grants MH065248 and MH074468 from the National Institute of Mental Health (NIMH), and by support from the Menninger and McNair Foundations. We are grateful for the support and collaboration of the South Carolina Department of Mental Health and the Charleston/Dorchester Community Mental Health Centers. We also wish to acknowledge important contributions by: Deborah C. Beidel, Jennifer Bennice, Todd C. Buckley, Victoria C. Cousins, Deborah DiNovo, Thom G. Hiers, Terence M. Keane, Mary Long, Chris Molnar, Kim T. Mueser, Emma Rhodes, Julie A. Sauvageot, Samuel M. Turner, Chris Wells, Eunsil Yim, and Heidi M. Zinzow.
PY - 2009/6
Y1 - 2009/6
N2 - In an open trial design, adults (n = 20) with posttraumatic stress disorder (PTSD) and either schizophrenia or schizoaffective disorder were treated via an 11-week cognitive-behavioral intervention for PTSD that consisted of education, anxiety management therapy, social skills training, and exposure therapy, provided at community mental health centers. Results offer preliminary hope for effective treatment of PTSD among adults with schizophrenia or schizoaffective disorder, especially among treatment completers (n = 13). Data showed significant PTSD symptom improvement, maintained at 3-month follow-up. Further, 12 of 13 completers no longer met criteria for PTSD or were considered treatment responders. Clinical outcomes for other targeted domains (e.g., anger, general mental health) also improved and were maintained at 3-month follow-up. Participants evidenced high treatment satisfaction, with no adverse events. Significant improvements were not noted on depression, general anxiety, or physical health status. Future directions include the need for randomized controlled trials and dissemination efforts.
AB - In an open trial design, adults (n = 20) with posttraumatic stress disorder (PTSD) and either schizophrenia or schizoaffective disorder were treated via an 11-week cognitive-behavioral intervention for PTSD that consisted of education, anxiety management therapy, social skills training, and exposure therapy, provided at community mental health centers. Results offer preliminary hope for effective treatment of PTSD among adults with schizophrenia or schizoaffective disorder, especially among treatment completers (n = 13). Data showed significant PTSD symptom improvement, maintained at 3-month follow-up. Further, 12 of 13 completers no longer met criteria for PTSD or were considered treatment responders. Clinical outcomes for other targeted domains (e.g., anger, general mental health) also improved and were maintained at 3-month follow-up. Participants evidenced high treatment satisfaction, with no adverse events. Significant improvements were not noted on depression, general anxiety, or physical health status. Future directions include the need for randomized controlled trials and dissemination efforts.
KW - Cognitive-behavioral therapy
KW - Exposure therapy
KW - PTSD
KW - Schizophrenia
KW - Severe mental illness (SMI)
KW - Trauma
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U2 - 10.1016/j.janxdis.2009.02.005
DO - 10.1016/j.janxdis.2009.02.005
M3 - Article
C2 - 19342194
AN - SCOPUS:64249122617
VL - 23
SP - 665
EP - 675
JO - Journal of Anxiety Disorders
JF - Journal of Anxiety Disorders
SN - 0887-6185
IS - 5
ER -