Evolution of the epidemiology of pneumococcal disease among Utah Children through the vaccine era

Krow Ampofo, Andrew T. Pavia, Chris R. Stockmann, Anne J. Blaschke, Hsin Yi Cindy Weng, Kent E. Korgenski, Judy Daly, Carrie L. Byington

Research output: Contribution to journalArticle

11 Scopus citations

Abstract

From 1996 to 2009, we analyzed changes in pneumococcal disease (PD) in Utah children aged <18 years using International Classification of Diseases, ninth revision coded hospital discharges. We observed a sustained decrease in the incidence of PD among children <5 years in 2001-2004 (-36%) and 2005-2009 (-34%) compared with 1996-2000 (pre-7-valent pneumococcal conjugate vaccine). Decreases were primarily in bacteremia, uncomplicated pneumonia, and meningitis. In contrast, significant increases in complicated pneumonia/empyema were noted in children <5 years (+95% and +85%) and 5 to 17 years (+2% and +70%). Despite decreases in PD among Utah children, complicated pneumonia/empyema has increased during the 7-valent pneumococcal conjugate vaccine era.

Original languageEnglish (US)
Pages (from-to)1100-1103
Number of pages4
JournalPediatric Infectious Disease Journal
Volume30
Issue number12
DOIs
StatePublished - Dec 2011

Keywords

  • PCV13
  • PCV7
  • Streptococcus pneumoniae
  • pneumococcal disease

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health
  • Microbiology (medical)
  • Infectious Diseases

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