Evolution of the epidemiology of pneumococcal disease among Utah Children through the vaccine era

Krow Ampofo; Andrew T. Pavia; Chris R. Stockmann; Anne J. Blaschke; Hsin Yi Cindy Weng; Kent E. Korgenski; Judy Daly; Carrie L. Byington

doi:10.1097/INF.0b013e318232ee3e

Evolution of the epidemiology of pneumococcal disease among Utah Children through the vaccine era

Krow Ampofo, Andrew T. Pavia, Chris R. Stockmann, Anne J. Blaschke, Hsin Yi Cindy Weng, Kent E. Korgenski, Judy Daly, Carrie L. Byington

Academic Institute

Research output: Contribution to journal › Article › peer-review

11 Scopus citations

Abstract

From 1996 to 2009, we analyzed changes in pneumococcal disease (PD) in Utah children aged <18 years using International Classification of Diseases, ninth revision coded hospital discharges. We observed a sustained decrease in the incidence of PD among children <5 years in 2001-2004 (-36%) and 2005-2009 (-34%) compared with 1996-2000 (pre-7-valent pneumococcal conjugate vaccine). Decreases were primarily in bacteremia, uncomplicated pneumonia, and meningitis. In contrast, significant increases in complicated pneumonia/empyema were noted in children <5 years (+95% and +85%) and 5 to 17 years (+2% and +70%). Despite decreases in PD among Utah children, complicated pneumonia/empyema has increased during the 7-valent pneumococcal conjugate vaccine era.

Original language	English (US)
Pages (from-to)	1100-1103
Number of pages	4
Journal	Pediatric Infectious Disease Journal
Volume	30
Issue number	12
DOIs	https://doi.org/10.1097/INF.0b013e318232ee3e
State	Published - Dec 2011

Keywords

PCV13
PCV7
Streptococcus pneumoniae
pneumococcal disease

ASJC Scopus subject areas

Pediatrics, Perinatology, and Child Health
Microbiology (medical)
Infectious Diseases

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10.1097/INF.0b013e318232ee3e

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title = "Evolution of the epidemiology of pneumococcal disease among Utah Children through the vaccine era",

abstract = "From 1996 to 2009, we analyzed changes in pneumococcal disease (PD) in Utah children aged <18 years using International Classification of Diseases, ninth revision coded hospital discharges. We observed a sustained decrease in the incidence of PD among children <5 years in 2001-2004 (-36%) and 2005-2009 (-34%) compared with 1996-2000 (pre-7-valent pneumococcal conjugate vaccine). Decreases were primarily in bacteremia, uncomplicated pneumonia, and meningitis. In contrast, significant increases in complicated pneumonia/empyema were noted in children <5 years (+95% and +85%) and 5 to 17 years (+2% and +70%). Despite decreases in PD among Utah children, complicated pneumonia/empyema has increased during the 7-valent pneumococcal conjugate vaccine era.",

keywords = "PCV13, PCV7, Streptococcus pneumoniae, pneumococcal disease",

author = "Krow Ampofo and Pavia, {Andrew T.} and Stockmann, {Chris R.} and Blaschke, {Anne J.} and Weng, {Hsin Yi Cindy} and Korgenski, {Kent E.} and Judy Daly and Byington, {Carrie L.}",

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AU - Ampofo, Krow

AU - Pavia, Andrew T.

AU - Stockmann, Chris R.

AU - Blaschke, Anne J.

AU - Weng, Hsin Yi Cindy

AU - Korgenski, Kent E.

AU - Daly, Judy

AU - Byington, Carrie L.

PY - 2011/12

Y1 - 2011/12

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AB - From 1996 to 2009, we analyzed changes in pneumococcal disease (PD) in Utah children aged <18 years using International Classification of Diseases, ninth revision coded hospital discharges. We observed a sustained decrease in the incidence of PD among children <5 years in 2001-2004 (-36%) and 2005-2009 (-34%) compared with 1996-2000 (pre-7-valent pneumococcal conjugate vaccine). Decreases were primarily in bacteremia, uncomplicated pneumonia, and meningitis. In contrast, significant increases in complicated pneumonia/empyema were noted in children <5 years (+95% and +85%) and 5 to 17 years (+2% and +70%). Despite decreases in PD among Utah children, complicated pneumonia/empyema has increased during the 7-valent pneumococcal conjugate vaccine era.

KW - PCV13

KW - PCV7

KW - Streptococcus pneumoniae

KW - pneumococcal disease

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Evolution of the epidemiology of pneumococcal disease among Utah Children through the vaccine era

Abstract

Keywords

ASJC Scopus subject areas

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