Evidence for parathyroid failure in magnesium deficiency

Constantine S. Anast; James M. Mohs; Sheldon L. Kaplan; Thomas W. Burns

doi:10.1126/science.177.4049.606

Evidence for parathyroid failure in magnesium deficiency

Constantine S. Anast, James M. Mohs, Sheldon L. Kaplan, Thomas W. Burns

Research Institute

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Abstract

Serum immunoreactive parathyroid hormone (IPTH) was low to nondetectable in spite of hypocalcemia in a patient with chronic magnesium deficiency. The administration of magnesium led to parallel increases in serum IPTH, serum calcium, and renal phosphate clearance. These findings support the view that magnesium depletion may result in impaired synthesis or release of parathyroid hormone in man, or both.

Original language	English (US)
Pages (from-to)	606-608
Number of pages	3
Journal	Science
Volume	177
Issue number	4049
DOIs	https://doi.org/10.1126/science.177.4049.606
State	Published - 1972

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title = "Evidence for parathyroid failure in magnesium deficiency",

abstract = "Serum immunoreactive parathyroid hormone (IPTH) was low to nondetectable in spite of hypocalcemia in a patient with chronic magnesium deficiency. The administration of magnesium led to parallel increases in serum IPTH, serum calcium, and renal phosphate clearance. These findings support the view that magnesium depletion may result in impaired synthesis or release of parathyroid hormone in man, or both.",

author = "Anast, {Constantine S.} and Mohs, {James M.} and Kaplan, {Sheldon L.} and Burns, {Thomas W.}",

year = "1972",

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AU - Mohs, James M.

AU - Kaplan, Sheldon L.

AU - Burns, Thomas W.

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Y1 - 1972

N2 - Serum immunoreactive parathyroid hormone (IPTH) was low to nondetectable in spite of hypocalcemia in a patient with chronic magnesium deficiency. The administration of magnesium led to parallel increases in serum IPTH, serum calcium, and renal phosphate clearance. These findings support the view that magnesium depletion may result in impaired synthesis or release of parathyroid hormone in man, or both.

AB - Serum immunoreactive parathyroid hormone (IPTH) was low to nondetectable in spite of hypocalcemia in a patient with chronic magnesium deficiency. The administration of magnesium led to parallel increases in serum IPTH, serum calcium, and renal phosphate clearance. These findings support the view that magnesium depletion may result in impaired synthesis or release of parathyroid hormone in man, or both.

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Evidence for parathyroid failure in magnesium deficiency

Abstract

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