Evidence for parathyroid failure in magnesium deficiency

Constantine S. Anast, James M. Mohs, Sheldon L. Kaplan, Thomas W. Burns

Research output: Contribution to journalArticlepeer-review

284 Scopus citations


Serum immunoreactive parathyroid hormone (IPTH) was low to nondetectable in spite of hypocalcemia in a patient with chronic magnesium deficiency. The administration of magnesium led to parallel increases in serum IPTH, serum calcium, and renal phosphate clearance. These findings support the view that magnesium depletion may result in impaired synthesis or release of parathyroid hormone in man, or both.

Original languageEnglish (US)
Pages (from-to)606-608
Number of pages3
Issue number4049
StatePublished - 1972

ASJC Scopus subject areas

  • General


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