Evaluation of Thimet 10-G for mutagenicity by 4 different genetic systems

T. K. Pandita

Research output: Contribution to journalArticle

10 Scopus citations

Abstract

The insecticide Thimet 10-G was tested for mutagenic activity by 4 different genetic systems. It was unable to induce gene mutation in Salmonella, transfection inhibition in Mycobacterium, micronuclei formation in mice, and sister-chromatid exchange (SCE) in human lymphocytes were evaluated. It caused in mice an increase in the ratio of normochromatic to polychromatic erythrocytes and in human lymphocytes a decrease in mitotic index and delay in cell cycle. The results indicate that the insecticide is not mutagenic in the 4 test systems used at present.

Original languageEnglish (US)
Pages (from-to)131-138
Number of pages8
JournalMutation Research/Genetic Toxicology
Volume171
Issue number2-3
DOIs
StatePublished - 1986

ASJC Scopus subject areas

  • Toxicology
  • Genetics

Fingerprint Dive into the research topics of 'Evaluation of Thimet 10-G for mutagenicity by 4 different genetic systems'. Together they form a unique fingerprint.

Cite this