Abstract
The insecticide Thimet 10-G was tested for mutagenic activity by 4 different genetic systems. It was unable to induce gene mutation in Salmonella, transfection inhibition in Mycobacterium, micronuclei formation in mice, and sister-chromatid exchange (SCE) in human lymphocytes were evaluated. It caused in mice an increase in the ratio of normochromatic to polychromatic erythrocytes and in human lymphocytes a decrease in mitotic index and delay in cell cycle. The results indicate that the insecticide is not mutagenic in the 4 test systems used at present.
Original language | English (US) |
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Pages (from-to) | 131-138 |
Number of pages | 8 |
Journal | Mutation Research/Genetic Toxicology |
Volume | 171 |
Issue number | 2-3 |
DOIs | |
State | Published - 1986 |
ASJC Scopus subject areas
- Toxicology
- Genetics