TY - JOUR
T1 - Evaluation of left ventricular wall motion, volumes, and ejection fraction by gated myocardial tomography with technetium 99m-labeled tetrofosmin
T2 - A comparison with cine magnetic resonance imaging
AU - Vaduganathan, Periyanan
AU - He, Zuo Xiang
AU - Wesley Vick, G.
AU - Mahmarian, John J.
AU - Verani, Mario S.
PY - 1999/1/1
Y1 - 1999/1/1
N2 - Background. Whether left ventricular function can be assessed accurately by gated single photon emission computed tomography (SPECT) in patients with myocardial infarction and severe perfusion defects is not well known. Methods and Results. Twenty-five patients with an acute myocardial infarction underwent 99mTc-labeled tetrofosmin (99mTc-tetrofosmin) gated SPECT and cine magnetic resonance imaging (MRI). Wall motion was assessed in 13 left ventricular segments using a 5-point scoring system ranging from 3 (normal) to -1 (dyskinetic). Exact agreement for wall motion scores between gated SPECT and MRI was excellent (92%, kappa = 0.82). Furthermore, correlations between the two techniques were also good for end-diastolic volume (r = 0.81, P < .0001), end-systolic volume (r = 0.92, P < .0001), and ejection fraction (r = 0.93, P < .0001). Conclusion. In patients with a recent myocardial infarction, 99mTc-tetrofosmin gated SPECT provides reliable evaluation of global and regional ventricular function and volumes.
AB - Background. Whether left ventricular function can be assessed accurately by gated single photon emission computed tomography (SPECT) in patients with myocardial infarction and severe perfusion defects is not well known. Methods and Results. Twenty-five patients with an acute myocardial infarction underwent 99mTc-labeled tetrofosmin (99mTc-tetrofosmin) gated SPECT and cine magnetic resonance imaging (MRI). Wall motion was assessed in 13 left ventricular segments using a 5-point scoring system ranging from 3 (normal) to -1 (dyskinetic). Exact agreement for wall motion scores between gated SPECT and MRI was excellent (92%, kappa = 0.82). Furthermore, correlations between the two techniques were also good for end-diastolic volume (r = 0.81, P < .0001), end-systolic volume (r = 0.92, P < .0001), and ejection fraction (r = 0.93, P < .0001). Conclusion. In patients with a recent myocardial infarction, 99mTc-tetrofosmin gated SPECT provides reliable evaluation of global and regional ventricular function and volumes.
KW - Cine magnetic resonance imaging
KW - Coronary artery disease
KW - Gated SPECT
KW - Myocardial infarction
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U2 - 10.1016/S1071-3581(99)90058-2
DO - 10.1016/S1071-3581(99)90058-2
M3 - Article
C2 - 10070835
SN - 1071-3581
VL - 6
SP - 3
EP - 10
JO - Journal of Nuclear Cardiology
JF - Journal of Nuclear Cardiology
IS - 1
ER -