Evaluation of left ventricular wall motion, volumes, and ejection fraction by gated myocardial tomography with technetium 99m-labeled tetrofosmin: A comparison with cine magnetic resonance imaging

Periyanan Vaduganathan, Zuo Xiang He, G. Wesley Vick, John J. Mahmarian, Mario S. Verani

Research output: Contribution to journalArticle

112 Scopus citations

Abstract

Background. Whether left ventricular function can be assessed accurately by gated single photon emission computed tomography (SPECT) in patients with myocardial infarction and severe perfusion defects is not well known. Methods and Results. Twenty-five patients with an acute myocardial infarction underwent 99mTc-labeled tetrofosmin (99mTc-tetrofosmin) gated SPECT and cine magnetic resonance imaging (MRI). Wall motion was assessed in 13 left ventricular segments using a 5-point scoring system ranging from 3 (normal) to -1 (dyskinetic). Exact agreement for wall motion scores between gated SPECT and MRI was excellent (92%, kappa = 0.82). Furthermore, correlations between the two techniques were also good for end-diastolic volume (r = 0.81, P < .0001), end-systolic volume (r = 0.92, P < .0001), and ejection fraction (r = 0.93, P < .0001). Conclusion. In patients with a recent myocardial infarction, 99mTc-tetrofosmin gated SPECT provides reliable evaluation of global and regional ventricular function and volumes.

Original languageEnglish (US)
Pages (from-to)3-10
Number of pages8
JournalJournal of Nuclear Cardiology
Volume6
Issue number1
DOIs
StatePublished - Jan 1 1999

Keywords

  • Cine magnetic resonance imaging
  • Coronary artery disease
  • Gated SPECT
  • Myocardial infarction

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine

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