Evaluation of a multidimensional measure of dyspepsia-related health for use in a randomized clinical trial

Karon F. Cook, Linda Rabeneck, Catherine J.M. Campbell, Nelda Wray

Research output: Contribution to journalArticle

25 Scopus citations

Abstract

In previous work, we developed a multidimensional measure of dyspepsia- related health. To evaluate the adequacy of this instrument as an outcome measure for a large-scale, multicenter, randomized clinical trial, we used Rasch analysis to address three questions: (1) Are the scales interval- level? (2) Do the scales measure precisely across the entire range of dyspepsia outcomes? (3) Do the scales' items have an optimal number of response categories? We found that the scales were not interval-level and that they did not measure effectively at low or high levels of the dyspepsia- related outcomes. Our results also suggest that patients were capable of discriminating among only four- to seven-item response categories. Further studies are needed to identify items that effectively measure high and low levels of dyspepsia-related outcomes and to validate that decreasing the number of response categories improves the psychometric properties of these scales.

Original languageEnglish (US)
Pages (from-to)381-392
Number of pages12
JournalJournal of Clinical Epidemiology
Volume52
Issue number5
DOIs
StatePublished - May 1999

Keywords

  • Dyspepsia
  • Helicobacter pylori
  • Outcome assessment (health care)
  • Psychometrics
  • Questionnaires
  • Treatment outcome

ASJC Scopus subject areas

  • Medicine(all)
  • Public Health, Environmental and Occupational Health
  • Epidemiology

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