Abstract
In this multicenter retrospective cohort study of over 1 million patients at 150 US hospitals, proton pump inhibitors increased the odds of a patient having hospital-onset Clostridium difcile infection as did third and fourth generation cephalosporins, carbapenems, and piperacillin/tazobactam. Tese fndings support appropriate prescribing of acid-suppression therapy and high-risk antibiotics.
Original language | English (US) |
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Pages (from-to) | 1957-1959 |
Number of pages | 3 |
Journal | Clinical Infectious Diseases |
Volume | 66 |
Issue number | 12 |
DOIs | |
State | Published - Jun 1 2018 |
Keywords
- Clostridium difcile infections
- acid suppression medication
- antibiotic therapy
- proton pump inhibitors
- risk factors
ASJC Scopus subject areas
- Microbiology (medical)
- Infectious Diseases