Evaluating the Risk Factors for Hospital-Onset Clostridium difficile Infections in a Large Healthcare System

Troy Watson, Jason Hickok, Sarah Fraker, Kimberly Korwek, Russell E. Poland, Edward Septimus

Research output: Contribution to journalArticlepeer-review

16 Scopus citations

Abstract

In this multicenter retrospective cohort study of over 1 million patients at 150 US hospitals, proton pump inhibitors increased the odds of a patient having hospital-onset Clostridium difcile infection as did third and fourth generation cephalosporins, carbapenems, and piperacillin/tazobactam. Tese fndings support appropriate prescribing of acid-suppression therapy and high-risk antibiotics.

Original languageEnglish (US)
Pages (from-to)1957-1959
Number of pages3
JournalClinical Infectious Diseases
Volume66
Issue number12
DOIs
StatePublished - Jun 1 2018

Keywords

  • acid suppression medication
  • antibiotic therapy
  • Clostridium difcile infections
  • proton pump inhibitors
  • risk factors

ASJC Scopus subject areas

  • Microbiology (medical)
  • Infectious Diseases

Fingerprint

Dive into the research topics of 'Evaluating the Risk Factors for Hospital-Onset Clostridium difficile Infections in a Large Healthcare System'. Together they form a unique fingerprint.

Cite this