Evaluating the Risk Factors for Hospital-Onset Clostridium difficile Infections in a Large Healthcare System

Troy Watson; Jason Hickok; Sarah Fraker; Kimberly Korwek; Russell E. Poland; Edward Septimus

doi:10.1093/cid/cix1112

Evaluating the Risk Factors for Hospital-Onset Clostridium difficile Infections in a Large Healthcare System

Troy Watson, Jason Hickok, Sarah Fraker, Kimberly Korwek, Russell E. Poland, Edward Septimus

Research output: Contribution to journal › Article › peer-review

24 Scopus citations

Abstract

In this multicenter retrospective cohort study of over 1 million patients at 150 US hospitals, proton pump inhibitors increased the odds of a patient having hospital-onset Clostridium difcile infection as did third and fourth generation cephalosporins, carbapenems, and piperacillin/tazobactam. Tese fndings support appropriate prescribing of acid-suppression therapy and high-risk antibiotics.

Original language	English (US)
Pages (from-to)	1957-1959
Number of pages	3
Journal	Clinical Infectious Diseases
Volume	66
Issue number	12
DOIs	https://doi.org/10.1093/cid/cix1112
State	Published - Jun 1 2018

Keywords

Clostridium difcile infections
acid suppression medication
antibiotic therapy
proton pump inhibitors
risk factors

ASJC Scopus subject areas

Microbiology (medical)
Infectious Diseases

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10.1093/cid/cix1112

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title = "Evaluating the Risk Factors for Hospital-Onset Clostridium difficile Infections in a Large Healthcare System",

abstract = "In this multicenter retrospective cohort study of over 1 million patients at 150 US hospitals, proton pump inhibitors increased the odds of a patient having hospital-onset Clostridium difcile infection as did third and fourth generation cephalosporins, carbapenems, and piperacillin/tazobactam. Tese fndings support appropriate prescribing of acid-suppression therapy and high-risk antibiotics.",

keywords = "Clostridium difcile infections, acid suppression medication, antibiotic therapy, proton pump inhibitors, risk factors",

author = "Troy Watson and Jason Hickok and Sarah Fraker and Kimberly Korwek and Poland, {Russell E.} and Edward Septimus",

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AU - Korwek, Kimberly

AU - Poland, Russell E.

AU - Septimus, Edward

PY - 2018/6/1

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N2 - In this multicenter retrospective cohort study of over 1 million patients at 150 US hospitals, proton pump inhibitors increased the odds of a patient having hospital-onset Clostridium difcile infection as did third and fourth generation cephalosporins, carbapenems, and piperacillin/tazobactam. Tese fndings support appropriate prescribing of acid-suppression therapy and high-risk antibiotics.

AB - In this multicenter retrospective cohort study of over 1 million patients at 150 US hospitals, proton pump inhibitors increased the odds of a patient having hospital-onset Clostridium difcile infection as did third and fourth generation cephalosporins, carbapenems, and piperacillin/tazobactam. Tese fndings support appropriate prescribing of acid-suppression therapy and high-risk antibiotics.

KW - Clostridium difcile infections

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KW - antibiotic therapy

KW - proton pump inhibitors

KW - risk factors

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Evaluating the Risk Factors for Hospital-Onset Clostridium difficile Infections in a Large Healthcare System

Abstract

Keywords

ASJC Scopus subject areas

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