Ethosomes for skin delivery

E. Touitou, Biana Godin

Research output: Contribution to journalReview article

23 Scopus citations

Abstract

It is well established that the structure and function of the skin prevent penetration of many therapeutic molecules to the site of their action in the deep cutaneous strata. This paper reviews the physicochemical characteristics, safety properties and mode of action of ethosomes, a delivery carrier designed to overcome the skin barrier, so that new and advanced dermal and regional therapies can be achieved. The performance of ethosomal systems is compared to different controls in in vitro, in vivo and clinical studies. Ethosomal systems containing various drugs for dermal and regional delivery including anti-infective and anti-inflammatory agents, as well as drugs targeted to pilosebaceous units are discussed.

Original languageEnglish (US)
Pages (from-to)303-308
Number of pages6
JournalJournal of Drug Delivery Science and Technology
Volume17
Issue number5
DOIs
StatePublished - Jan 1 2007

Keywords

  • Dermal delivery
  • Enhancer
  • Ethosomes
  • Skin
  • Skin infection
  • Vesicular carrier

ASJC Scopus subject areas

  • Pharmaceutical Science

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