Establishment of modified abdominal heart transplantation model in rats

S. Yu, Xiaoshun He, Y. Ma

Research output: Contribution to journalArticle

Abstract

OBJECTIVE: To investigate the techniques of establishment of abdominal heart transplantation model in rats and modify the procedure to make it more stable and improve the success rate. METHODS: Heterotopic abdominal heart transplantations of Wistar and SD rats were performed by using Ono's method with modification of preparation of recipients, donor cardiectomy and donor transplantations. RESULTS: One hundred heart transplantations were performed, among which 90 were successful. The success rate was 90%. CONCLUSION: This modified Ono's method can shorten the ischemia time and recipient abdominal aorta occlusion time, make vessel anastomosis easier and increase the success rate of operation. It is a stable and reliable model of heart transplantations in rats.

Original languageEnglish (US)
Pages (from-to)327-329
Number of pages3
JournalBeijing da xue xue bao. Yi xue ban = Journal of Peking University. Health sciences
Volume40
Issue number3
StatePublished - Jan 1 2008

ASJC Scopus subject areas

  • Medicine(all)

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