Abstract
OBJECTIVE: To investigate the techniques of establishment of abdominal heart transplantation model in rats and modify the procedure to make it more stable and improve the success rate. METHODS: Heterotopic abdominal heart transplantations of Wistar and SD rats were performed by using Ono's method with modification of preparation of recipients, donor cardiectomy and donor transplantations. RESULTS: One hundred heart transplantations were performed, among which 90 were successful. The success rate was 90%. CONCLUSION: This modified Ono's method can shorten the ischemia time and recipient abdominal aorta occlusion time, make vessel anastomosis easier and increase the success rate of operation. It is a stable and reliable model of heart transplantations in rats.
Original language | English (US) |
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Pages (from-to) | 327-329 |
Number of pages | 3 |
Journal | Beijing da xue xue bao. Yi xue ban = Journal of Peking University. Health sciences |
Volume | 40 |
Issue number | 3 |
State | Published - Jan 1 2008 |
ASJC Scopus subject areas
- Medicine(all)