OBJECTIVE: To investigate the techniques of establishment of abdominal heart transplantation model in rats and modify the procedure to make it more stable and improve the success rate. METHODS: Heterotopic abdominal heart transplantations of Wistar and SD rats were performed by using Ono's method with modification of preparation of recipients, donor cardiectomy and donor transplantations. RESULTS: One hundred heart transplantations were performed, among which 90 were successful. The success rate was 90%. CONCLUSION: This modified Ono's method can shorten the ischemia time and recipient abdominal aorta occlusion time, make vessel anastomosis easier and increase the success rate of operation. It is a stable and reliable model of heart transplantations in rats.
|Original language||English (US)|
|Number of pages||3|
|Journal||Beijing da xue xue bao. Yi xue ban = Journal of Peking University. Health sciences|
|State||Published - Jan 1 2008|
ASJC Scopus subject areas