Establishing a novel C. elegans model to investigate the role of autophagy in amyotrophic lateral sclerosis

Keyphrases

• Amyotrophic Lateral Sclerosis 100%
• Autophagy 100%
• Motor Neuron 100%
• Caenorhabditis Elegans 100%
• SOD1G93A 83%
• Axon Guidance 50%
• Daf-2 50%
• Autophagic 33%
• Worm 33%
• Transgenic Worms 33%
• SOD1 Aggregation 33%
• Motor Defects 33%
• Quantitative PCR 16%
• Fluorescence Microscopy 16%
• Autophagosome 16%
• Protein Aggregation 16%
• Age-dependent 16%
• Motor Function 16%
• Superoxide Dismutase 1 (SOD1) 16%
• Mutant Forms 16%
• Over 80 16%
• Paralysis 16%
• Zn-superoxide Dismutase 16%
• Mutant SOD1 16%
• SOD1 mutation 16%
• GABAergic Motor Neuron 16%
• LGG-1 16%
• BEC-1 16%

Biochemistry, Genetics and Molecular Biology

• Autophagy 100%
• Motor Neuron 100%
• Caenorhabditis elegans 100%
• SOD1 100%
• Axon Guidance 42%
• Daf-2 42%
• Transgenics 28%
• Anti-Thymocyte Globulin 28%
• Real-Time Polymerase Chain Reaction 14%
• Protein Aggregation 14%
• Autophagosome 14%
• Fluorescence Microscopy 14%
• Superoxide Dismutase 14%
• Motor Performance 14%

Neuroscience

• Amyotrophic Lateral Sclerosis 100%
• Autophagy 100%
• SOD1 100%
• Caenorhabditis elegans 100%
• Axon Guidance 42%
• Daf-2 42%
• Anti-Thymocyte Globulin 28%
• Real-Time Polymerase Chain Reaction 14%
• Copper Zinc Superoxide Dismutase 14%
• Protein Aggregation 14%