Erythrocytosis and marked leukocytosis in overlapping myeloproliferative diseases

Todd D. Shenkenberg, Caroline C. Waddell, Lawrence Rice

Research output: Contribution to journalArticle

3 Scopus citations

Abstract

Chronic myelogenous leukemia (CML) and polycythemia vera (PV) are included in the spectrum of diseases referred to as myeloproliferative disorders. Patients with CML are frequently anemic at the time of diagnosis. Occasionally, however, erythrocytosis may be present in patients with CML, suggesting a diagnosis of PV. Mild neutrophilic leukocytosis is frequent in PV but marked leukocytosis is uncommon. We describe two patients with erythrocytosis and marked leukocytosis subsequently classified as CML and PV by the use of leukocyte alkaline phosphatase (LAP) scores and cytogenetic studies to detect the Philadelphia (Ph1) chromosome.

Original languageEnglish (US)
Pages (from-to)868-869
Number of pages2
JournalSouthern Medical Journal
Volume75
Issue number7
DOIs
StatePublished - Jan 1 1982

ASJC Scopus subject areas

  • Medicine(all)

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