TY - JOUR
T1 - Erythrocytosis and marked leukocytosis in overlapping myeloproliferative diseases
AU - Shenkenberg, Todd D.
AU - Waddell, Caroline C.
AU - Rice, Lawrence
PY - 1982/1/1
Y1 - 1982/1/1
N2 - Chronic myelogenous leukemia (CML) and polycythemia vera (PV) are included in the spectrum of diseases referred to as myeloproliferative disorders. Patients with CML are frequently anemic at the time of diagnosis. Occasionally, however, erythrocytosis may be present in patients with CML, suggesting a diagnosis of PV. Mild neutrophilic leukocytosis is frequent in PV but marked leukocytosis is uncommon. We describe two patients with erythrocytosis and marked leukocytosis subsequently classified as CML and PV by the use of leukocyte alkaline phosphatase (LAP) scores and cytogenetic studies to detect the Philadelphia (Ph1) chromosome.
AB - Chronic myelogenous leukemia (CML) and polycythemia vera (PV) are included in the spectrum of diseases referred to as myeloproliferative disorders. Patients with CML are frequently anemic at the time of diagnosis. Occasionally, however, erythrocytosis may be present in patients with CML, suggesting a diagnosis of PV. Mild neutrophilic leukocytosis is frequent in PV but marked leukocytosis is uncommon. We describe two patients with erythrocytosis and marked leukocytosis subsequently classified as CML and PV by the use of leukocyte alkaline phosphatase (LAP) scores and cytogenetic studies to detect the Philadelphia (Ph1) chromosome.
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U2 - 10.1097/00007611-198207000-00027
DO - 10.1097/00007611-198207000-00027
M3 - Article
C2 - 6953606
AN - SCOPUS:0020328020
VL - 75
SP - 868
EP - 869
JO - Southern Medical Journal
JF - Southern Medical Journal
SN - 0038-4348
IS - 7
ER -