Epithelioid glioblastoma presenting as massive intracerebral hemorrhage: Case report and review of the literature

Brandon Liebelt, Zain Boghani, Hidehiro Takei, Steve Fung, Gavin Britz

Research output: Contribution to journalArticlepeer-review

10 Scopus citations

Abstract

Background: Glioblastoma multiforme (GBM) is a malignant transformation of glial tissue, which presents as intradural, intraaxial lesions with heterogenous contrast enhancement and mass effect. Intratumoral hemorrhage is a common finding in GBM although it is frequently asymptomatic. Massive, symptomatic, intratumoral hemorrhage is uncommon and poses a diagnostic challenge. Case Description: Here we discuss a case of GBM, which initially presented as massive, symptomatic intracerebral hemorrhage with underlying mass. Due to size of the hemorrhage and poor neurological status the patient was taken to the operating room for evacuation of this hematoma. On pathology, the mass was found to be epithelioid glioblastoma. Conclusion: Identification and diagnosis of GBM is generally straightforward. In certain circumstances, the presentation of GBM can vary from the routine. The above case demonstrates how pitfalls in diagnosis can be avoided in order to initiate appropriate therapy.

Original languageEnglish (US)
Pages (from-to)S97-S100
JournalSurgical Neurology International
Volume6
Issue number3
DOIs
StatePublished - Apr 1 2015

Keywords

  • Epithelioid
  • Glioblastoma
  • Intratumoral hemorrhage

ASJC Scopus subject areas

  • Surgery
  • Clinical Neurology

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