Epithelial lining methods in esophageal repair: A comparative study using pedicle flaps in cats

G. R. Tobin, D. T. Netscher, R. A. Williams, J. D. Richardson, L. M. Flint, J. B. Sharp, H. C. Polk

Research output: Contribution to journalArticlepeer-review

11 Scopus citations


Methods of restoring luminal lining in repair of partial-circumferential esophageal defects were evaluated to compare incidences of strictures and fistulas and quality of surface lining. In cats 50% and 67% circumferential esophageal defects were repaired by direct closure or pedicle flats (latissimus dorsi) that were unlined (lining restored by epithelialization from wound margins) or that carried lining of normal skin (myocutaneous flaps), skin grafts, or mucosal grafts. Repairs were evaluated for esophagocutaneous fistulas, luminal stricture, flap luminal surface area, and quality of epithelial surface after 6 weeks after surgery. Direct closure of 50% circumferential defects was as satisfactory as any flap repair method. Direct closure of 67% circumferential defects caused high incidences of fistulas and strictures, which were lessened by flap reconstructions. Among flap lining methods, normal skin (myocutaneous flaps) gave the lowest incidence of fistulas and strictures and the highest surface quality, but a high incidence of skin paddle loss occurred in this model. Split-thickness epithelial grafts were nearly as satisfactory as myocutaneous flaps, and less lining loss occurred. Epithelialization of unlined flaps gave the poorest results since lining was thin and often incomplete, and wound contraction produced loss of surface area and strictures. The findings are discussed from a perspective of wound healing physiology, and implications for clinical application are presented.

Original languageEnglish (US)
Pages (from-to)158-165
Number of pages8
Issue number2
StatePublished - 1985

ASJC Scopus subject areas

  • Surgery


Dive into the research topics of 'Epithelial lining methods in esophageal repair: A comparative study using pedicle flaps in cats'. Together they form a unique fingerprint.

Cite this