Episodic twice-daily treatment for recurrent genital herpes

Leonard Harry Goldberg, R. Kaufman, M. A. Conant, J. Sperber, M. L. Allen, M. Illeman, P. S. Donohew, S. Chapman

Research output: Contribution to journalArticlepeer-review

13 Scopus citations


A new dosage regimen of orally administered acyclovir, 800 mg twice daily for five days, for the treatment of recurrent genital herpes was compared with the standard dosage of 200 mg given five times per day. A double-blind study of 157 patients was used to evaluate the safety and efficacy of both regimens. The new regimen was well tolerated, more convenient, and as effective as the standard dosage. In male patients, the new regimen may be more effective than the standard regimen of 200 mg given five times per day to treat lesions that are already present.

Original languageEnglish (US)
Pages (from-to)10-13
Number of pages4
JournalAmerican Journal of Medicine
Issue number2 A
StatePublished - Jan 1 1988

ASJC Scopus subject areas

  • Medicine(all)


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