Epidemic alphaviruses: Ecology, emergence and outbreaks

Sasha R. Azar, Rafael K. Campos, Nicholas A. Bergren, Vidyleison N. Camargos, Shannan L. Rossi

    Research output: Contribution to journalReview articlepeer-review

    28 Scopus citations


    Over the past century, the emergence/reemergence of arthropod-borne zoonotic agents has been a growing public health concern. In particular, agents from the genus Alphavirus pose a significant risk to both animal and human health. Human alphaviral disease presents with either arthritogenic or encephalitic manifestations and is associated with significant morbidity and/or mortality. Unfortunately, there are presently no vaccines or antiviral measures approved for human use. The present review examines the ecology, epidemiology, disease, past outbreaks, and potential to cause contemporary outbreaks for several alphavirus pathogens.

    Original languageEnglish (US)
    Article number1167
    Pages (from-to)1-35
    Number of pages35
    Issue number8
    StatePublished - Aug 2020


    • Alphavirus
    • Enzootic
    • Epizootic
    • Mosquitoes
    • Outbreaks
    • Togaviridae

    ASJC Scopus subject areas

    • Microbiology
    • Microbiology (medical)
    • Virology


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