Enterococcus faecalis mutations affecting virulence in the Caenorhabditis elegans model host

Arash Maadani; Kristina A. Fox; Elftherios Mylonakis; Danielle A. Garsin

doi:10.1128/IAI.01372-06

Enterococcus faecalis mutations affecting virulence in the Caenorhabditis elegans model host

Arash Maadani, Kristina A. Fox, Elftherios Mylonakis, Danielle A. Garsin

Research output: Contribution to journal › Article › peer-review

66 Scopus citations

Abstract

Enterococcus faecalis transposon insertion mutants were screened for attenuated killing of the nematode model host Caenorhabditis elegans. The genes disrupted in the attenuated mutants encode a variety of factors including transcriptional regulators, transporters, and damage control and repair systems. Five of nine mutants tested were attenuated in a mouse peritonitis model.

Original language	English (US)
Pages (from-to)	2634-2637
Number of pages	4
Journal	Infection and Immunity
Volume	75
Issue number	5
DOIs	https://doi.org/10.1128/IAI.01372-06
State	Published - May 2007

ASJC Scopus subject areas

Parasitology
Microbiology
Immunology
Infectious Diseases

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10.1128/IAI.01372-06

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abstract = "Enterococcus faecalis transposon insertion mutants were screened for attenuated killing of the nematode model host Caenorhabditis elegans. The genes disrupted in the attenuated mutants encode a variety of factors including transcriptional regulators, transporters, and damage control and repair systems. Five of nine mutants tested were attenuated in a mouse peritonitis model.",

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Enterococcus faecalis mutations affecting virulence in the Caenorhabditis elegans model host

Abstract

ASJC Scopus subject areas

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