Enterococcus faecalis mutations affecting virulence in the Caenorhabditis elegans model host

Arash Maadani; Kristina A. Fox; Elftherios Mylonakis; Danielle A. Garsin

doi:10.1128/IAI.01372-06

Enterococcus faecalis mutations affecting virulence in the Caenorhabditis elegans model host

Arash Maadani, Kristina A. Fox, Elftherios Mylonakis, Danielle A. Garsin

Research output: Contribution to journal › Article › peer-review

64 Scopus citations

Abstract

Enterococcus faecalis transposon insertion mutants were screened for attenuated killing of the nematode model host Caenorhabditis elegans. The genes disrupted in the attenuated mutants encode a variety of factors including transcriptional regulators, transporters, and damage control and repair systems. Five of nine mutants tested were attenuated in a mouse peritonitis model.

Original language	English (US)
Pages (from-to)	2634-2637
Number of pages	4
Journal	Infection and Immunity
Volume	75
Issue number	5
DOIs	https://doi.org/10.1128/IAI.01372-06
State	Published - May 2007

ASJC Scopus subject areas

Parasitology
Microbiology
Immunology
Infectious Diseases

Access to Document

10.1128/IAI.01372-06

Cite this

@article{54ad6d4d14ac46afa3aac17cb4a1ce49,

title = "Enterococcus faecalis mutations affecting virulence in the Caenorhabditis elegans model host",

abstract = "Enterococcus faecalis transposon insertion mutants were screened for attenuated killing of the nematode model host Caenorhabditis elegans. The genes disrupted in the attenuated mutants encode a variety of factors including transcriptional regulators, transporters, and damage control and repair systems. Five of nine mutants tested were attenuated in a mouse peritonitis model.",

author = "Arash Maadani and Fox, \{Kristina A.\} and Elftherios Mylonakis and Garsin, \{Danielle A.\}",

year = "2007",

month = may,

doi = "10.1128/IAI.01372-06",

language = "English (US)",

volume = "75",

pages = "2634--2637",

journal = "Infection and Immunity",

issn = "0019-9567",

publisher = "American Society for Microbiology",

number = "5",

}

TY - JOUR

T1 - Enterococcus faecalis mutations affecting virulence in the Caenorhabditis elegans model host

AU - Maadani, Arash

AU - Fox, Kristina A.

AU - Mylonakis, Elftherios

AU - Garsin, Danielle A.

PY - 2007/5

Y1 - 2007/5

N2 - Enterococcus faecalis transposon insertion mutants were screened for attenuated killing of the nematode model host Caenorhabditis elegans. The genes disrupted in the attenuated mutants encode a variety of factors including transcriptional regulators, transporters, and damage control and repair systems. Five of nine mutants tested were attenuated in a mouse peritonitis model.

AB - Enterococcus faecalis transposon insertion mutants were screened for attenuated killing of the nematode model host Caenorhabditis elegans. The genes disrupted in the attenuated mutants encode a variety of factors including transcriptional regulators, transporters, and damage control and repair systems. Five of nine mutants tested were attenuated in a mouse peritonitis model.

UR - https://www.scopus.com/pages/publications/34248386490

UR - https://www.scopus.com/inward/citedby.url?scp=34248386490&partnerID=8YFLogxK

U2 - 10.1128/IAI.01372-06

DO - 10.1128/IAI.01372-06

M3 - Article

C2 - 17307944

AN - SCOPUS:34248386490

SN - 0019-9567

VL - 75

SP - 2634

EP - 2637

JO - Infection and Immunity

JF - Infection and Immunity

IS - 5

ER -

Enterococcus faecalis mutations affecting virulence in the Caenorhabditis elegans model host

Abstract

ASJC Scopus subject areas

Access to Document

Other files and links

Fingerprint

Cite this