Enrolling decisionally incapacitated subjects in neuropsychiatric research

Joseph Fins, F. G. Miller

Research output: Contribution to journalReview articlepeer-review

29 Scopus citations


This paper discusses the National Bioethics Advisory Commission's (NBAC's) report on research involving persons with mental disorders that may affect decisionmaking capacity. After placing the NBAC recommendations into their historic context, the authors propose a strategy' to enroll decisionally incapacitated subjects into neuropsychiatric research. The authors maintained that their proposed consensus model for research authorization, utilizing subject advocates, fosters valuable clinical research while protecting potentially vulnerable subjects.

Original languageEnglish (US)
Pages (from-to)32-42
Number of pages11
JournalCNS spectrums
Issue number10
StatePublished - Jan 1 2000

ASJC Scopus subject areas

  • Clinical Neurology
  • Psychiatry and Mental health


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