Enhanced MRI relaxivity of aquated Gd3+ ions by carboxyphenylated water-dispersed graphene nanoribbons

Ayrat Gizzatov; Vazrik Keshishian; Adem Guven; Ayrat M. Dimiev; Feifei Qu; Raja Muthupillai; Paolo Decuzzi; Robert G. Bryant; James M. Tour; Lon J. Wilson

doi:10.1039/c3nr06026h

Enhanced MRI relaxivity of aquated Gd³⁺ ions by carboxyphenylated water-dispersed graphene nanoribbons

Ayrat Gizzatov, Vazrik Keshishian, Adem Guven, Ayrat M. Dimiev, Feifei Qu, Raja Muthupillai, Paolo Decuzzi, Robert G. Bryant, James M. Tour, Lon J. Wilson

Academic Institute

Research output: Contribution to journal › Article › peer-review

37 Scopus citations

Abstract

The present study demonstrates that highly water-dispersed graphene nanoribbons dispersed by carboxyphenylated substituents and conjugated to aquated Gd³⁺ ions can serve as a high-performance contrast agent (CA) for applications in T₁- and T₂-weighted magnetic resonance imaging (MRI) with relaxivity (r_1,2) values outperforming currently-available clinical CAs by up to 16 times for r₁ and 21 times for r₂. This journal is

Original language	English (US)
Pages (from-to)	3059-3063
Number of pages	5
Journal	Nanoscale
Volume	6
Issue number	6
DOIs	https://doi.org/10.1039/c3nr06026h
State	Published - Mar 21 2014

ASJC Scopus subject areas

Materials Science(all)

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abstract = "The present study demonstrates that highly water-dispersed graphene nanoribbons dispersed by carboxyphenylated substituents and conjugated to aquated Gd3+ ions can serve as a high-performance contrast agent (CA) for applications in T1- and T2-weighted magnetic resonance imaging (MRI) with relaxivity (r1,2) values outperforming currently-available clinical CAs by up to 16 times for r1 and 21 times for r2. This journal is",

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AU - Gizzatov, Ayrat

AU - Keshishian, Vazrik

AU - Guven, Adem

AU - Dimiev, Ayrat M.

AU - Qu, Feifei

AU - Muthupillai, Raja

AU - Decuzzi, Paolo

AU - Bryant, Robert G.

AU - Tour, James M.

AU - Wilson, Lon J.

PY - 2014/3/21

Y1 - 2014/3/21

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AB - The present study demonstrates that highly water-dispersed graphene nanoribbons dispersed by carboxyphenylated substituents and conjugated to aquated Gd3+ ions can serve as a high-performance contrast agent (CA) for applications in T1- and T2-weighted magnetic resonance imaging (MRI) with relaxivity (r1,2) values outperforming currently-available clinical CAs by up to 16 times for r1 and 21 times for r2. This journal is

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Enhanced MRI relaxivity of aquated Gd³⁺ ions by carboxyphenylated water-dispersed graphene nanoribbons

Abstract

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