Enhanced active metabolite generation and platelet inhibition with prasugrel compared to clopidogrel regardless of genotype in thienopyridine metabolic pathways

Oscar Ö Braun, Dominick J. Angiolillo, Jose L. Ferreiro, Joseph A. Jakubowski, Kenneth J. Winters, Mark B. Effron, Suman Duvvuru, Timothy M. Costigan, Scott S. Sundseth, Joseph R. Walker, Jorge F. Saucedo, Neal S. Kleiman, Christoph Varenhorst

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Medicine & Life Sciences