Engineering the assemblies of biomaterial nanocarriers for delivery of multiple theranostic agents with enhanced antitumor efficacy

Hai Wang, Yan Wu, Ruifang Zhao, Guangjun Nie

Research output: Contribution to journalArticlepeer-review

81 Scopus citations

Abstract

The rapid development of nanotechnology holds great promise for revolutionizing the current landscape of tumor drug delivery. However, one of the biggest challenges is developing a simple nanocarrier platform to co-deliver various therapeutic agents. Here, a strategy for fabricating nanocarriers with many desirable features is demonstrated. The resulting nanoparticles achieve both high antitumor efficacy and effective inhibition of tumor metastasis with minimal side effects.

Original languageEnglish (US)
Pages (from-to)1616-1622
Number of pages7
JournalAdvanced Materials
Volume25
Issue number11
DOIs
StatePublished - Mar 20 2013

Keywords

  • cancer metastasis
  • combination therapy
  • drug delivery
  • multifunctional nanoparticles

ASJC Scopus subject areas

  • Materials Science(all)
  • Mechanics of Materials
  • Mechanical Engineering

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