Engineering the abio-bio interface to enable more than moore in functional bioelectronics

O. Karunwi, A. N. Wilson, C. Kotanen, A. Guiseppi-Elie

Research output: Contribution to journalArticlepeer-review

16 Scopus citations


The need for biocompatible, low impedance abio-to-bio interfaces suitable for implantable bioactive devices has led us to develop electroconductive hydrogels. Conductive electroactive polymers (CEPs) are one dimensional organic semiconductors synthesized from aromatic monomers into extended pi-conjugated polymers. The synthesis of CEP's, in association with hydrogels, produces a class of hybrid materials with the conductivity of the CEP and inherent biocompatibility of the hydrogel. CEPs provide a means for the additive electrodeposition of biorecognition molecules to specific nano- and micron-dimensioned metallic and semiconducting sites on microfabricated metallic or semiconductorMEMS devices. Through judicious engineering of repeat unit chemistry, polymer architecture, crosslink density and microstructure, the mechanical, transport and surface properties may be controlled. Implanted, thesematerials enable programmed lowvoltage electro-release of factors suitable formitigating inflammatory response. Finally, these hydrogels can accommodate supramolecular assemblies of CNTs and enzymes supporting direct electron transfer for generation-3 biosensors and implantable biofuel cells.

Original languageEnglish (US)
Pages (from-to)B60-B65
JournalJournal of the Electrochemical Society
Issue number4
StatePublished - 2013

ASJC Scopus subject areas

  • Electronic, Optical and Magnetic Materials
  • Renewable Energy, Sustainability and the Environment
  • Condensed Matter Physics
  • Surfaces, Coatings and Films
  • Electrochemistry
  • Materials Chemistry


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