Engineering the abio-bio interface to enable more than moore in functional bioelectronics

Anthony Guiseppi-Elie, C. Kotanen, O. Karunwi, A. N. Wilson

Research output: Chapter in Book/Report/Conference proceedingConference contribution

1 Scopus citations

Abstract

The need for biocompatible, low impedance abio-to-bio interfaces suitable for implantable bioactive devices has led us to develop electroconductive hydrogels. Conductive electroactive polymers (CEPs) are one dimensional organic semiconductors synthesized from aromatic monomers into extended pi-conjugated polymers. The synthesis of CEPs in association with hydrogels produces class of hybrid materials with the conductivity of the CEP and inherent biocompatibility of the hydrogel. CEPs provide a means for the additive electrodeposition of biorecognition molecules to specific nano- and micron-dimensioned metallic and semiconducting sites on microfabricated metallic or semiconductor MEMS devices. Through judicious engineering of repeat unit chemistry, polymer architecture, crosslink density and microstructure, the mechanical, transport and surface properties may be controlled. Implanted, these materials enable programmed low voltage electro-release of factors suitable for mitigating inflammatory response. Finally, these hydrogels can accommodate supramolecular assemblies of CNTs and enzymes supporting direct electron transfer for generation-3 biosensors and implantable biofuel cells.

Original languageEnglish (US)
Title of host publicationInternational Symposium on Functional Diversification of Semiconductor Electronics
Pages13-29
Number of pages17
Volume50
Edition14
DOIs
StatePublished - Dec 1 2012
EventSymposium on More than Moore - 222nd ECS Meeting/PRiME 2012 - Honolulu, HI, United States
Duration: Oct 7 2012Oct 12 2012

Other

OtherSymposium on More than Moore - 222nd ECS Meeting/PRiME 2012
CountryUnited States
CityHonolulu, HI
Period10/7/1210/12/12

ASJC Scopus subject areas

  • Engineering(all)

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