Endovascular techniques in limb salvage: cutting, cryo, brachy, and drug-eluting balloons.

Mark G. Davies, Javier E. Anaya-Ayala

Research output: Contribution to journalReview articlepeer-review

13 Scopus citations


The complex pathophysiology response to injury of the lower-extremity arteries has prompted the development of several unique balloon technologies to overcome initial technical failures and short-term intimal hyperplasia. Cryoplasty alters the cellular and mechanical properties of the vessel wall during angioplasty. Cutting balloons incise the wall, preventing elastic recoil and allowing expansion of the lumen at a lower pressure, thus limiting barotrauma. Drug-eluting balloons actively transfer inhibitory compounds to the wall during the initial therapy, while brachytherapy balloons allow for localized delivery of radiation to inhibit the proliferative response seen after angioplasty. These platforms provide unique means to enhance immediate and short-term results and also reduce stent usage in the lower extremity.

Original languageEnglish (US)
Pages (from-to)69-72
Number of pages4
JournalMethodist DeBakey cardiovascular journal
Issue number2
StatePublished - Apr 2013

ASJC Scopus subject areas

  • Medicine(all)


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