TY - JOUR
T1 - Endovascular techniques in limb salvage
T2 - cutting, cryo, brachy, and drug-eluting balloons.
AU - Davies, Mark G.
AU - Anaya-Ayala, Javier E.
N1 - Copyright:
Copyright 2020 Elsevier B.V., All rights reserved.
PY - 2013/4
Y1 - 2013/4
N2 - The complex pathophysiology response to injury of the lower-extremity arteries has prompted the development of several unique balloon technologies to overcome initial technical failures and short-term intimal hyperplasia. Cryoplasty alters the cellular and mechanical properties of the vessel wall during angioplasty. Cutting balloons incise the wall, preventing elastic recoil and allowing expansion of the lumen at a lower pressure, thus limiting barotrauma. Drug-eluting balloons actively transfer inhibitory compounds to the wall during the initial therapy, while brachytherapy balloons allow for localized delivery of radiation to inhibit the proliferative response seen after angioplasty. These platforms provide unique means to enhance immediate and short-term results and also reduce stent usage in the lower extremity.
AB - The complex pathophysiology response to injury of the lower-extremity arteries has prompted the development of several unique balloon technologies to overcome initial technical failures and short-term intimal hyperplasia. Cryoplasty alters the cellular and mechanical properties of the vessel wall during angioplasty. Cutting balloons incise the wall, preventing elastic recoil and allowing expansion of the lumen at a lower pressure, thus limiting barotrauma. Drug-eluting balloons actively transfer inhibitory compounds to the wall during the initial therapy, while brachytherapy balloons allow for localized delivery of radiation to inhibit the proliferative response seen after angioplasty. These platforms provide unique means to enhance immediate and short-term results and also reduce stent usage in the lower extremity.
UR - http://www.scopus.com/inward/record.url?scp=84895661662&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84895661662&partnerID=8YFLogxK
U2 - 10.14797/mdcj-9-2-69
DO - 10.14797/mdcj-9-2-69
M3 - Review article
C2 - 23805337
AN - SCOPUS:84895661662
SN - 1947-6094
VL - 9
SP - 69
EP - 72
JO - Methodist DeBakey cardiovascular journal
JF - Methodist DeBakey cardiovascular journal
IS - 2
ER -