Endovascular Reperfusion of Acute Large Vessel Occlusion Stroke

Anqi Luo, Vivek Misra, Lee A. Birnbaum

Research output: Chapter in Book/Report/Conference proceedingChapter


Acute stroke treatment continues to evolve with optimization of systemic intravenous thrombolysis and endovascular mechanical thrombectomy (MT) for intracranial large vessel occlusion (LVO). Neurointerventional techniques to achieve reperfusion in acute LVO stroke initially involved local intra-arterial infusion of thrombolytic agents. The subsequent development of MT devices has resulted in more complete and faster arterial recanalization while maintaining patient safety. Today, MT is standard of care for LVO stroke up to 24 h from last known well. In this chapter, we discuss various endovascular recanalization techniques for LVO stroke with illustrative cases.

Original languageEnglish (US)
Title of host publicationCurrent Clinical Neurology
PublisherHumana Press
Number of pages12
StatePublished - 2022

Publication series

NameCurrent Clinical Neurology
ISSN (Print)1559-0585
ISSN (Electronic)2524-4043


  • Direct aspiration
  • Intra-arterial fibrinolysis
  • Mechanical thrombectomy
  • Stentriever
  • Stroke

ASJC Scopus subject areas

  • Clinical Neurology


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