TY - JOUR
T1 - Endogenous fungal endophthalmitis
T2 - Causative organisms, management strategies, and visual acuity outcomes
AU - Lingappan, Ahila
AU - Wykoff, Charles C.
AU - Albini, Thomas A.
AU - Miller, Darlene
AU - Pathengay, Avinash
AU - Davis, Janet L.
AU - Flynn, Harry W.
PY - 2012/1
Y1 - 2012/1
N2 - To report the causative organisms, management strategies, and visual outcomes in endogenous fungal endophthalmitis. Observational case series. Microbiologic and medical records were reviewed retrospectively for all patients with culture-positive endogenous fungal endophthalmitis between January 1, 1990, and July 1, 2009. Study criteria were met in 65 eyes of 51 patients with mean follow-up of 18 months. Yeasts were the most common causative organism in 38 (75%) patients compared with molds in 13 (25%) patients. Retinal detachment occurred in 17 eyes (26%). Visual acuity of 20/200 or better was present in 28 (56%) eyes with yeasts and in 5 (33%) eyes with molds at the last follow-up. Yeasts were the most common cause of culture-proven unilateral or bilateral endogenous fungal endophthalmitis. Endogenous fungal endophthalmitis generally is associated with poor visual acuity outcomes, especially when caused by molds. Retinal detachment is a frequent occurrence during follow-up.
AB - To report the causative organisms, management strategies, and visual outcomes in endogenous fungal endophthalmitis. Observational case series. Microbiologic and medical records were reviewed retrospectively for all patients with culture-positive endogenous fungal endophthalmitis between January 1, 1990, and July 1, 2009. Study criteria were met in 65 eyes of 51 patients with mean follow-up of 18 months. Yeasts were the most common causative organism in 38 (75%) patients compared with molds in 13 (25%) patients. Retinal detachment occurred in 17 eyes (26%). Visual acuity of 20/200 or better was present in 28 (56%) eyes with yeasts and in 5 (33%) eyes with molds at the last follow-up. Yeasts were the most common cause of culture-proven unilateral or bilateral endogenous fungal endophthalmitis. Endogenous fungal endophthalmitis generally is associated with poor visual acuity outcomes, especially when caused by molds. Retinal detachment is a frequent occurrence during follow-up.
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U2 - 10.1016/j.ajo.2011.06.020
DO - 10.1016/j.ajo.2011.06.020
M3 - Article
C2 - 21917234
AN - SCOPUS:83555176157
VL - 153
SP - 162-166.e1
JO - American Journal of Ophthalmology
JF - American Journal of Ophthalmology
SN - 0002-9394
IS - 1
ER -