TY - JOUR
T1 - Endocervical Adenocarcinoma, Gross Examination, and Processing, Including Intraoperative Evaluation
T2 - Recommendations From the International Society of Gynecological Pathologists
AU - Parra-Herran, Carlos
AU - Malpica, Anais
AU - Oliva, Esther
AU - Zannoni, Gian Franco
AU - Ramirez, Pedro T.
AU - Rabban, Joseph T.
N1 - Publisher Copyright:
© 2021 Lippincott Williams and Wilkins. All rights reserved.
PY - 2021/3/1
Y1 - 2021/3/1
N2 - The International Society of Gynecological Pathologists (ISGyP) Endocervical Adenocarcinoma Project aims to provide evidence-based guidance for the pathologic evaluation, classification, and reporting of endocervical adenocarcinoma. This review presents the recommendations pertaining to gross evaluation and intraoperative consultation of specimens obtained from patients in the setting of cervical cancer. The recommendations are the product of review of published peer-reviewed evidence, international guidelines and institutional grossing manuals, as well as deliberation within this working group. The discussion presented herein details the approach to the different specimen types encountered in practice: loop electrosurgical excision procedure, cone, trachelectomy, radical hysterectomy, pelvic exenteration, and lymphadenectomy specimens. Guidelines for intraoperative evaluation of trachelectomy and sentinel lymph node specimens are also addressed. Correlation with ISGyP recommendations on cancer staging, which appear as a separate review in this issue, is also included when appropriate. While conceived in the framework of endocervical adenocarcinoma, most of the discussion and recommendations can also be applied to other cervical malignancies.
AB - The International Society of Gynecological Pathologists (ISGyP) Endocervical Adenocarcinoma Project aims to provide evidence-based guidance for the pathologic evaluation, classification, and reporting of endocervical adenocarcinoma. This review presents the recommendations pertaining to gross evaluation and intraoperative consultation of specimens obtained from patients in the setting of cervical cancer. The recommendations are the product of review of published peer-reviewed evidence, international guidelines and institutional grossing manuals, as well as deliberation within this working group. The discussion presented herein details the approach to the different specimen types encountered in practice: loop electrosurgical excision procedure, cone, trachelectomy, radical hysterectomy, pelvic exenteration, and lymphadenectomy specimens. Guidelines for intraoperative evaluation of trachelectomy and sentinel lymph node specimens are also addressed. Correlation with ISGyP recommendations on cancer staging, which appear as a separate review in this issue, is also included when appropriate. While conceived in the framework of endocervical adenocarcinoma, most of the discussion and recommendations can also be applied to other cervical malignancies.
KW - Cone
KW - Endocervical adenocarcinoma
KW - Hysterectomy
KW - LEEP
KW - Lymph node dissection
KW - Specimen processing
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U2 - 10.1097/PGP.0000000000000745
DO - 10.1097/PGP.0000000000000745
M3 - Article
C2 - 33570862
AN - SCOPUS:85101446706
SN - 0277-1691
VL - 40
SP - S24-S47
JO - International Journal of Gynecological Pathology
JF - International Journal of Gynecological Pathology
IS - suppl 1
ER -