Emerging prevention and treatment strategies to control COVID-19

Vipul K. Singh, Abhishek Mishra, Shubhra Singh, Premranjan Kumar, Manisha Singh, Chinnaswamy Jagannath, Arshad Khan

Research output: Contribution to journalReview article

Abstract

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the causative agent of coronavirus disease 2019 (COVID-19), has now become a serious global threat after inflicting more than 8 million infections and 425,000 deaths in less than 6 months. Currently, no definitive treatment or prevention therapy exists for COVID-19. The unprecedented rise of this pandemic has rapidly fueled research efforts to discover and develop new vaccines and treatment strategies against this novel coronavirus. While hundreds of vaccines/therapeutics are still in the preclinical or early stage of clinical development, a few of them have shown promising results in controlling the infection. Here, in this review, we discuss the promising vaccines and treatment options for COVID-19, their challenges, and potential alternative strategies.

Original languageEnglish (US)
Article number501
Pages (from-to)1-16
Number of pages16
JournalPathogens
Volume9
Issue number6
DOIs
StatePublished - Jun 2020

Keywords

  • COVID-19
  • Convalescent plasma
  • Drug repurposing
  • SARS-CoV-2
  • Stem cell therapy
  • Vaccine interventions

ASJC Scopus subject areas

  • Immunology and Allergy
  • Molecular Biology
  • Immunology and Microbiology(all)
  • Microbiology (medical)
  • Infectious Diseases

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  • Cite this

    Singh, V. K., Mishra, A., Singh, S., Kumar, P., Singh, M., Jagannath, C., & Khan, A. (2020). Emerging prevention and treatment strategies to control COVID-19. Pathogens, 9(6), 1-16. [501]. https://doi.org/10.3390/pathogens9060501