TY - JOUR
T1 - Emerging applications of nanomedicine for the diagnosis and treatment of cardiovascular diseases
AU - Godin, Biana
AU - Sakamoto, Jason H.
AU - Serda, Rita E.
AU - Grattoni, Alessandro
AU - Bouamrani, Ali
AU - Ferrari, Mauro
N1 - Funding Information:
Matt Landry is gratefully recognized for his artistry in the preparation of Figure 1 . The authors acknowledge financial support from the following sources: DODW81XWH-09-1-0212, DODW81XWH-07-2-0101; NASA NNJ06HE06A; NIH RO1CA128797, NIH – R33 CA122864, NIH U54CA143837 and State of Texas, Emerging Technology Fund and by the grant-awarding organizations: Department of Defense (DoD), National Institutes Health (NIH) and National Aeronautics and Space Administration (NASA).
Copyright:
Copyright 2010 Elsevier B.V., All rights reserved.
PY - 2010/5
Y1 - 2010/5
N2 - Nanomedicine is an emerging field that utilizes nanotechnology concepts for advanced therapy and diagnostics. This convergent discipline merges research areas such as chemistry, biology, physics, mathematics and engineering. It therefore bridges the gap between molecular and cellular interactions, and has the potential to revolutionize medicine. This review presents recent developments in nanomedicine research poised to have an important impact on the treatment of cardiovascular disease. This will occur through improvement of the diagnosis and therapy of cardiovascular disorders as atherosclerosis, restenosis and myocardial infarction. Specifically, we discuss the use of nanoparticles for molecular imaging and advanced therapeutics, specially designed drug eluting stents and in vivo/ex vivo early detection techniques.
AB - Nanomedicine is an emerging field that utilizes nanotechnology concepts for advanced therapy and diagnostics. This convergent discipline merges research areas such as chemistry, biology, physics, mathematics and engineering. It therefore bridges the gap between molecular and cellular interactions, and has the potential to revolutionize medicine. This review presents recent developments in nanomedicine research poised to have an important impact on the treatment of cardiovascular disease. This will occur through improvement of the diagnosis and therapy of cardiovascular disorders as atherosclerosis, restenosis and myocardial infarction. Specifically, we discuss the use of nanoparticles for molecular imaging and advanced therapeutics, specially designed drug eluting stents and in vivo/ex vivo early detection techniques.
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U2 - 10.1016/j.tips.2010.01.003
DO - 10.1016/j.tips.2010.01.003
M3 - Review article
C2 - 20172613
AN - SCOPUS:77952551701
VL - 31
SP - 199
EP - 205
JO - Trends in Pharmacological Sciences
JF - Trends in Pharmacological Sciences
SN - 0165-6147
IS - 5
ER -